{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:13:23Z","timestamp":1740165203932,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic> Case report describing an eight-month-old infant presenting with intermittent esotropia and irritability who was found to have malignant (grade 4) hypertensive retinopathy and mid-aortic syndrome.<jats:italic> Methods.<\/jats:italic> Visual acuity was 6\/140 in the right eye and not recordable in the left eye. Blood pressure was as high as 230\/120\u2009mmHg. Fundoscopy revealed bilateral optic disc swelling, macular stars, and serous retinal detachment in the left eye, findings that are consistent with malignant (grade 4) hypertensive retinopathy. CT abdominal angiogram revealed a severe mid-aortic syndrome with occlusion of the abdominal aorta at T12.<jats:italic> Results.<\/jats:italic> The patient was treated with medical management of his hypertension, improving the subretinal exudate. Binocular visual acuity improved to 6\/9.5 over 9 months. There was a persistent left relative afferent pupillary defect and moderate left esotropia.<jats:italic> Conclusion.<\/jats:italic> This is the first reported case of malignant hypertensive retinopathy in an infant with concomitant mid-aortic occlusion. The authors emphasize the need for an ophthalmological and pediatric examination in a child presenting with intermittent squint and irritability. The esotropia was found to be a false localizing sign of raised intracranial pressure secondary to the severe mid-aortic syndrome.<\/jats:p>","DOI":"10.1155\/2016\/8162687","type":"journal-article","created":{"date-parts":[[2016,10,5]],"date-time":"2016-10-05T17:23:10Z","timestamp":1475688190000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Malignant Hypertensive Retinopathy in an Infant with Mid-Aortic Occlusion"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3548-2148","authenticated-orcid":true,"given":"Lawrence J.","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Save Sight Institute, Sydney, NSW, Australia"},{"name":"Sydney Medical School, University of Sydney, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Children\u2019s Hospital at Westmead, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.","family":"Winlaw","sequence":"additional","affiliation":[{"name":"Sydney Medical School, University of Sydney, Sydney, NSW, Australia"},{"name":"The Heart Centre for Children, The Children\u2019s Hospital at Westmead, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig E.","family":"Donaldson","sequence":"additional","affiliation":[{"name":"Sydney Medical School, University of Sydney, Sydney, NSW, Australia"},{"name":"Department of Ophthalmology, The Children\u2019s Hospital at Westmead, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922809339385"},{"issue":"3","key":"2","first-page":"223","volume":"7","year":"1993","journal-title":"Journal of Human Hypertension"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2008.01126.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199612263352607"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.5.401"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70401-9"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1177\/088307389400900208"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra032865"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/8162687.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/8162687.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/8162687.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T17:06:53Z","timestamp":1476724013000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2016\/8162687\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":8,"alternative-id":["8162687","8162687"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8162687","relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"type":"print","value":"2090-6722"},{"type":"electronic","value":"2090-6730"}],"subject":[],"published":{"date-parts":[[2016]]}}}