{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T11:09:57Z","timestamp":1761995397618,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Beijing Municipal Training Foundation for Highly Qualified and Technological Talents of Health System","award":["2014-3-038","2009B38"],"award-info":[{"award-number":["2014-3-038","2009B38"]}]},{"name":"Beijing Novel Star Project in Science and Technology of China","award":["2014-3-038","2009B38"],"award-info":[{"award-number":["2014-3-038","2009B38"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. The aim of this study was to investigate the association between COPD and major adverse cardiovascular and cerebral events (MACCE) in patients undergoing percutaneous coronary intervention (PCI).<jats:italic>Methods<\/jats:italic>. 2,362 patients who underwent PCI were included in this study. Subjects were divided into 2 groups: with COPD (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">233<\/mml:mn><\/mml:math>) and without COPD (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>n<\/mml:mi><\/mml:mrow><\/mml:math>= 2,129). Cox proportional hazards models were analyzed to determine the effect of COPD on the incidence of MACCE.<jats:italic>Results<\/jats:italic>. The patients with COPD were older (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>) and were more likely to be current smokers (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0<\/mml:mn><mml:mn fontstyle=\"italic\">2<\/mml:mn><\/mml:math>) and have had hypertension (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0<\/mml:mn><mml:mn fontstyle=\"italic\">2<\/mml:mn><\/mml:math>) and diabetes mellitus (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0<\/mml:mn><mml:mn fontstyle=\"italic\">1<\/mml:mn><\/mml:math>). Prevalence of serious cardiovascular comorbidity was higher in the patients with COPD, including a history of MI (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0<\/mml:mn><mml:mn fontstyle=\"italic\">2<\/mml:mn><\/mml:math>) and HF (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>). Compared with non-COPD group, the COPD group showed a higher risk of all-cause death (hazard ratio (HR): 2.45,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>), cardiac death (HR: 2.53,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.00<\/mml:mn><mml:mn fontstyle=\"italic\">02<\/mml:mn><\/mml:math>), MI (HR: 1.387,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0<\/mml:mn><mml:mn fontstyle=\"italic\">27<\/mml:mn><\/mml:math>), and HF (HR: 2.25,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>).<jats:italic>Conclusions<\/jats:italic>. Patients with CAD and concomitant COPD are associated with a higher incidence of MACCE (all-cause death, cardiac death, MI, and HF) compared to patients without COPD. The patients with a history of COPD have higher in-hospital and long-term mortality rates than those without COPD after PCI.<\/jats:p>","DOI":"10.1155\/2016\/8212459","type":"journal-article","created":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T21:05:51Z","timestamp":1480539951000},"page":"1-6","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Chronic Obstructive Pulmonary Disease on Long-Term Outcome in Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2956-4056","authenticated-orcid":true,"given":"Ming","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-Jiu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Eastern Hospital of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-ping","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Provincial Clinical Medical College, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang-Hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Tongji Hospital, Tongji University, Shanghai 200065, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huai-Sheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Shenzhen People\u2019s Hospital, The Second Clinical Hospital of Jinan University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Xiao","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8068-8498","authenticated-orcid":true,"given":"Li-juan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Eastern Hospital of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/mcp.0000000000000145"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200703-456so"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.115725"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2014.974736"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/140.3_Pt_2.S76"},{"key":"6","first-page":"337","volume":"4","year":"2009","journal-title":"International Journal of Chronic Obstructive Pulmonary Disease"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.4.2068"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.6.1952"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1177\/0003319712458145"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.04.010"},{"key":"11","first-page":"1353","volume":"10","year":"2015","journal-title":"International Journal of Chronic Obstructive Pulmonary Disease"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv737"},{"issue":"11","key":"13","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/S0735-1097(02)01877-6","volume":"39","year":"2002","journal-title":"Journal of the American College of Cardiology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-2644"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-0300"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2313"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2003.019588"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12412"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0106163"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200707-1080oc"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-008-1103-4"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-015-0068-z"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.11.0180"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.5.3618"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12181"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150586"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201203-0455pp"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa041747"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2029"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/8212459.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/8212459.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/8212459.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T04:54:19Z","timestamp":1498366459000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2016\/8212459\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":29,"alternative-id":["8212459","8212459"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8212459","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"type":"print","value":"2314-6133"},{"type":"electronic","value":"2314-6141"}],"subject":[],"published":{"date-parts":[[2016]]}}}