{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:46:16Z","timestamp":1774478776677,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Acute clavicle osteomyelitis in children is rare representing &lt;3% of osteomyelitis cases. We treated a 12-year-old boy who presented with acute pain in the right clavicle and high fever for 4 days. MRI showed abnormal signal in the right clavicle with periosteal reaction.<jats:italic>Staphylococcus aureus<\/jats:italic>isolated from blood was susceptible to methicillin, clindamycin, and macrolides. Clindamycin was given intravenously for 3\u2009wks and orally for another 3\u2009wks with no recurrence. We reviewed clavicle osteomyelitis cases in children searching PubMed English literature. From a total of 89 studies retrieved, only 6 fulfilled the criteria and were analyzed. Sixteen patients (56% female) were included with a median age of 9\u2009yrs (range 2\u2009wks\u201316\u2009yrs). Osteomyelitis was hematogenous in most cases, with<jats:italic>S. aureus<\/jats:italic>being the most frequent cause, isolated from either blood or tissue. Symptoms included fever, swelling, and localized bone tenderness. Antimicrobial therapy lasted for 4\u201312 weeks (median 7.5). Three patients required drainage or curettage. Recurrence occurred in 1\/16 cases (6.2%) and persistence of symptoms occurred to 2\/16 cases (12.5%) reported before 90s with unknown antimicrobial susceptibility of the pathogen. Acute clavicle osteomyelitis mainly affects older children and has generally good prognosis.<jats:italic>Staphylococcus aureus<\/jats:italic>is most commonly implicated and surgery may be needed.<\/jats:p>","DOI":"10.1155\/2016\/8252318","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T16:12:26Z","timestamp":1480954346000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["A Rare Case of Clavicle Osteomyelitis in a Child and Literature Review"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3972-1510","authenticated-orcid":true,"given":"Elisavet-Anna","family":"Chrysochoou","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit, 3rd Department of Pediatrics, Medical Faculty, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charalampos","family":"Antachopoulos","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, 3rd Department of Pediatrics, Medical Faculty, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Badekas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, General Hospital of Serres, Serres, Central Macedonia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0202-364X","authenticated-orcid":true,"given":"Emmanuel","family":"Roilides","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, 3rd Department of Pediatrics, Medical Faculty, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1213956"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(82)80066-4"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00004694-199707000-00011"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/bpo.0b013e3181c11992"},{"key":"5","first-page":"17","volume":"58","year":"1968","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/bf00347213"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/bf00197463"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-198709000-00014"},{"issue":"125","key":"9","first-page":"24","year":"1977","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3109\/17453677408989675"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2005.02.005"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1988.01860210066017"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3928\/0090-4481-20060201-11"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2006.09.009"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s13244-012-0186-8"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-003-2029-y"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16727-5"},{"issue":"2","key":"18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1586\/eri.09.130","volume":"8","year":"2010","journal-title":"Expert Review of Anti-Infective Therapy"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-2-16"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2016\/8252318.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2016\/8252318.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2016\/8252318.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T01:17:29Z","timestamp":1498353449000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cripe\/2016\/8252318\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":19,"alternative-id":["8252318","8252318"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8252318","relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}