{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:40:43Z","timestamp":1789562443285,"version":"build-2803163510"},"reference-count":18,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Lipopolysaccharide (LPS) and endothelin- (ET-) 1 may aggravate portal hypertension by increasing intrahepatic resistance and splanchnic blood flow. In the portal vein, after TIPS shunting, LPS and ET-1 were significantly decreased. Our study suggests that TIPS can benefit cirrhotic patients not only in high hemodynamics related variceal bleeding but also in intestinal bacterial translocation associated complications such as endotoxemia.<\/jats:p>","DOI":"10.1155\/2016\/8341030","type":"journal-article","created":{"date-parts":[[2016,1,31]],"date-time":"2016-01-31T16:05:17Z","timestamp":1454256317000},"page":"1-5","source":"Crossref","is-referenced-by-count":10,"title":["Systemic and Splanchnic Lipopolysaccharide and Endothelin-1 Plasma Levels in Liver Cirrhosis before and after Transjugular Intrahepatic Portosystemic Shunt"],"prefix":"10.1155","volume":"2016","author":[{"given":"Jiaxiang","family":"Meng","sequence":"first","affiliation":[{"name":"Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuofei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Fan","sequence":"additional","affiliation":[{"name":"Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baochen","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changsheng","family":"He","sequence":"additional","affiliation":[{"name":"Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingjiang","family":"Wu","sequence":"additional","affiliation":[{"name":"Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27343"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.10.042"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1159\/000375352"},{"issue":"1","key":"4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/MAJ.0000000000000403","volume":"349","year":"2015","journal-title":"The American Journal of the Medical Sciences"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23383"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/545018"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/01.rvi.0000094596.83406.19"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2006.08.026"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32834a75dc"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.06.042"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230x-11-107"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.12.011"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00336.2005"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-012-0660-6"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2015.05.025"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199508103330607"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9622"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.07.044"}],"container-title":["Gastroenterology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2016\/8341030.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2016\/8341030.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2016\/8341030.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T00:53:36Z","timestamp":1498265616000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/grp\/2016\/8341030\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":18,"alternative-id":["8341030","8341030"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8341030","relation":{},"ISSN":["1687-6121","1687-630X"],"issn-type":[{"value":"1687-6121","type":"print"},{"value":"1687-630X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}