{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:14:12Z","timestamp":1793085252226,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01DA034952"],"award-info":[{"award-number":["R01DA034952"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["T32MH019733"],"award-info":[{"award-number":["T32MH019733"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01DA034952"],"award-info":[{"award-number":["R01DA034952"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["T32MH019733"],"award-info":[{"award-number":["T32MH019733"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Natural language processing (NLP) and machine learning were used to predict suicidal ideation and heightened psychiatric symptoms among adults recently discharged from psychiatric inpatient or emergency room settings in Madrid, Spain. Participants responded to structured mental and physical health instruments at multiple follow-up points. Outcome variables of interest were suicidal ideation and psychiatric symptoms (GHQ-12). Predictor variables included structured items (e.g., relating to sleep and well-being) and responses to one unstructured question, \u201chow do you feel today?\u201d We compared NLP-based models using the unstructured question with logistic regression prediction models using structured data. The PPV, sensitivity, and specificity for NLP-based models of suicidal ideation were 0.61, 0.56, and 0.57, respectively, compared to 0.73, 0.76, and 0.62 of structured data-based models. The PPV, sensitivity, and specificity for NLP-based models of heightened psychiatric symptoms (GHQ-12 \u2265 4) were 0.56, 0.59, and 0.60, respectively, compared to 0.79, 0.79, and 0.85 in structured models. NLP-based models were able to generate relatively high predictive values based solely on responses to a simple general mood question. These models have promise for rapidly identifying persons at risk of suicide or psychological distress and could provide a low-cost screening alternative in settings where lengthy structured item surveys are not feasible.<\/jats:p>","DOI":"10.1155\/2016\/8708434","type":"journal-article","created":{"date-parts":[[2016,9,26]],"date-time":"2016-09-26T17:35:47Z","timestamp":1474911347000},"page":"1-8","source":"Crossref","is-referenced-by-count":155,"title":["Novel Use of Natural Language Processing (NLP) to Predict Suicidal Ideation and Psychiatric Symptoms in a Text-Based Mental Health Intervention in Madrid"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0135-0806","authenticated-orcid":true,"given":"Benjamin L.","family":"Cook","sequence":"first","affiliation":[{"name":"Health Equity Research Laboratory, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 1035 Cambridge Street, Suite 26, Cambridge, MA 02141, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"Progovac","sequence":"additional","affiliation":[{"name":"Health Equity Research Laboratory, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 1035 Cambridge Street, Suite 26, Cambridge, MA 02141, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Chen","sequence":"additional","affiliation":[{"name":"Wired Informatics, 265 Franklin Street, Suite 1702, Boston, MA 02110, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Mullin","sequence":"additional","affiliation":[{"name":"Health Equity Research Laboratory, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 1035 Cambridge Street, Suite 26, Cambridge, MA 02141, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry","family":"Hou","sequence":"additional","affiliation":[{"name":"Health Equity Research Laboratory, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 1035 Cambridge Street, Suite 26, Cambridge, MA 02141, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6963-6555","authenticated-orcid":true,"given":"Enrique","family":"Baca-Garcia","sequence":"additional","affiliation":[{"name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Avda. Reyes Cat\u00f3licos 2, 28040 Madrid, Spain"},{"name":"Autonomous University of Madrid, Ciudad Universitaria de Cantoblanco, 28049 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"9859","key":"1","first-page":"2095","volume":"380","year":"1990","journal-title":"The Lancet"},{"key":"2","first-page":"1","volume":"63, supplement 4","year":"2014","journal-title":"MMWR Surveillance Summaries"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2015.12.063"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-016-0774-5"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1590\/S1516-44462005000200011","volume":"27","year":"2005","journal-title":"Revista Brasileira de Psiquiatria"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2012.02247.x"},{"key":"8","year":"2014"},{"key":"9","year":"2014"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2014.0099"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.m1794"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1017\/s0033291711000997"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1204"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.m3028"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1754"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2014-002733"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.19.1845"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002626"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.m2848"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12384"},{"issue":"2","key":"21","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1197\/jamia.M1074","volume":"10","year":"2003","journal-title":"Journal of the American Medical Informatics Association"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2006.06.003"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.m2142"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2005.11.004"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700021644"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1186\/1745-0179-4-10"},{"issue":"4","key":"29","first-page":"839","volume":"20","year":"2008","journal-title":"Psicothema"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1159\/000376585"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1136\/jamia.2009.001560"},{"issue":"1","key":"32","first-page":"e151","volume":"22","year":"2015","journal-title":"Journal of the American Medical Informatics Association"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/8708434.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/8708434.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/8708434.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T19:44:43Z","timestamp":1498333483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2016\/8708434\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":29,"alternative-id":["8708434","8708434"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8708434","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"value":"1748-670X","type":"print"},{"value":"1748-6718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}