{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T21:49:31Z","timestamp":1781128171500,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pulmonology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Amebiasis is a parasitic infection caused by the protozoan<jats:italic>Entamoeba histolytica<\/jats:italic>. While most infections are asymptomatic, the disease could manifest clinically as amebic dysentery and\/or extraintestinal invasion in the form of amebic liver abscess or other more rare manifestations such as pulmonary, cardiac, or brain involvement. Herein we are reporting a case of a 24-year-old male with history of Down syndrome who presented with severe right side pneumonia complicated with multicystic empyema resistant to regular medical therapy. Further investigation revealed a positive pleural fluid for<jats:italic>E. histolytica<\/jats:italic>cysts and trophozoites. The patient was diagnosed with primary pleuropulmonary amebiasis and he responded promptly to surgical drainage and metronidazole therapy. In patients from endemic areas all physicians should keep a high index of suspicion of amebiasis as a cause of pulmonary disease.<\/jats:p>","DOI":"10.1155\/2016\/8709347","type":"journal-article","created":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T17:00:46Z","timestamp":1468170046000},"page":"1-4","source":"Crossref","is-referenced-by-count":9,"title":["Primary Pulmonary Amebiasis Complicated with Multicystic Empyema"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0183-1634","authenticated-orcid":true,"given":"Ali","family":"Zakaria","sequence":"first","affiliation":[{"name":"Istishari Hospital, Department of Internal Medicine, Division of Pulmonology, Amman 11183, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayan","family":"Al-Share","sequence":"additional","affiliation":[{"name":"Istishari Hospital, Department of Internal Medicine, Division of Pulmonology, Amman 11183, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Al Asad","sequence":"additional","affiliation":[{"name":"Istishari Hospital, Department of Internal Medicine, Division of Pulmonology, Amman 11183, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.5.1275"},{"issue":"1","key":"3","first-page":"13","volume":"18","year":"1997","journal-title":"Epidemiological Bulletin"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2009.06.008"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(03)12830-9"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00004-07"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-5231(01)00008-9"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199410000-00004"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-5231(01)00008-9"},{"issue":"2","key":"8","first-page":"96","volume":"7","year":"2003","journal-title":"Brazilian Journal of Infectious Diseases"},{"issue":"2","key":"10","first-page":"106","volume":"12","year":"1997","journal-title":"Seminars in Respiratory Infections"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.4065\/83.10.1154"},{"issue":"4","key":"12","doi-asserted-by":"crossref","first-page":"414","DOI":"10.4269\/ajtmh.1998.58.414","volume":"58","year":"1998","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2005.12.012"},{"issue":"2","key":"14","first-page":"203","volume":"142","year":"1985","journal-title":"Western Journal of Medicine"}],"container-title":["Case Reports in Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2016\/8709347.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2016\/8709347.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2016\/8709347.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T14:09:35Z","timestamp":1498313375000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cripu\/2016\/8709347\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":14,"alternative-id":["8709347","8709347"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8709347","relation":{},"ISSN":["2090-6846","2090-6854"],"issn-type":[{"value":"2090-6846","type":"print"},{"value":"2090-6854","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}