{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:28:16Z","timestamp":1765546096703},"reference-count":7,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Wernicke\u2019s encephalopathy is caused by severe thiamine deficiency; it is mostly observed in alcoholic patients. We report the case of a 28-year-old woman, at 17 weeks of gestational age, with severe hyperemesis gravidarum. She presented with disturbance of consciousness, nystagmus, ophthalmoplegia, and ataxia. The resonance magnetic imagery showed bilaterally symmetrical hyperintensities of thalamus and periaqueductal area. The case was managed with very large doses of thiamine. The diagnosis of Wernicke\u2019s encephalopathy was confirmed later by a low thiamine serum level. The patient was discharged home on day 46 with mild ataxia and persistent nystagmus. Wernicke\u2019s encephalopathy is a rare complication of hyperemesis gravidarum. It should be diagnosed as early as possible to prevent long-term neurological sequela or death. Thiamine supplementation in pregnant women with prolonged vomiting should be initiated, especially before parenteral dextrose infusion. Early thiamine replacement will reduce maternal morbidity and fetal loss rate.<\/jats:p>","DOI":"10.1155\/2016\/8783932","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T21:03:56Z","timestamp":1455656636000},"page":"1-3","source":"Crossref","is-referenced-by-count":6,"title":["Wernicke\u2019s Encephalopathy Complicating Hyperemesis during Pregnancy"],"prefix":"10.1155","volume":"2016","author":[{"given":"Mohamed Adnane","family":"Berdai","sequence":"first","affiliation":[{"name":"Department of Obstetric and Pediatric Anaesthesiology and Intensive Care, University Hospital Hassan II, 30070 Fez, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smael","family":"Labib","sequence":"additional","affiliation":[{"name":"Department of Obstetric and Pediatric Anaesthesiology and Intensive Care, University Hospital Hassan II, 30070 Fez, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustapha","family":"Harandou","sequence":"additional","affiliation":[{"name":"Department of Obstetric and Pediatric Anaesthesiology and Intensive Care, University Hospital Hassan II, 30070 Fez, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2011.03.001"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(07)70104-7"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.10.018"},{"issue":"2","key":"4","first-page":"43","volume":"9","year":"2002","journal-title":"Malaysian Journal of Medical Sciences"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.03153.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000206336.08794.65"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.05.004"}],"container-title":["Case Reports in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2016\/8783932.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2016\/8783932.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2016\/8783932.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T18:13:47Z","timestamp":1469556827000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cricc\/2016\/8783932\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":7,"alternative-id":["8783932","8783932"],"URL":"https:\/\/doi.org\/10.1155\/2016\/8783932","relation":{},"ISSN":["2090-6420","2090-6439"],"issn-type":[{"value":"2090-6420","type":"print"},{"value":"2090-6439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}