{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T19:37:19Z","timestamp":1787945839509,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Medicine"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The diagnosis and treatment of massive pericardial effusion and cardiac tamponade have evolved over the years with a tendency towards a more comprehensive diagnostic workup and less traumatic intervention.<jats:italic>Method<\/jats:italic>. We reviewed and analysed the data of 32 consecutive patients who underwent surgery on account of massive pericardial effusion and cardiac tamponade in a semiurban university hospital in Nigeria from February 2010 to February 2016.<jats:italic>Results<\/jats:italic>. The majority of patients (34.4%) were between 31 and 40 years. Fourteen patients (43.8%) presented with clinical and echocardiographic feature of cardiac tamponade. The majority of patients (59.4%) presented with haemorrhagic pericardial effusion and the average volume of fluid drained intraoperatively was 846\u2009mL\u2009\u2009\u00b1 67\u2009mL. Pericardium was thickened in 50% of cases. Subxiphoid pericardiostomy was performed under local anaesthesia in 28 cases. No postoperative recurrence was observed; however 5 patients developed features of constrictive pericarditis. The relationship between pericardial thickness and development of pericardial constriction was statistically significant (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.004<\/mml:mn><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. Subxiphoid pericardiostomy is a very effective way of treating massive pericardial effusion. Removing tube after adequate drainage (50\u2009mL\/day) and treatment of primary pathology are key to preventing recurrence. There is also a need to follow up patients to detect pericardial constriction especially those with thickened pericardium.<\/jats:p>","DOI":"10.1155\/2016\/8917954","type":"journal-article","created":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T21:01:19Z","timestamp":1468962079000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Surgical Management of Massive Pericardial Effusion and Predictors for Development of Constrictive Pericarditis in a Resource Limited Setting"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4057-2295","authenticated-orcid":true,"given":"Emeka B.","family":"Kesieme","sequence":"first","affiliation":[{"name":"Department of Surgery, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter O.","family":"Okokhere","sequence":"additional","affiliation":[{"name":"Department of Medicine, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher Ojemiega","family":"Iruolagbe","sequence":"additional","affiliation":[{"name":"Department of Medicine, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Odike","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifford","family":"Owobu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theophilus","family":"Akhigbe","sequence":"additional","affiliation":[{"name":"Department of Radiology, Irrua Specialist Teaching Hospital, PMB 8, Irrua, Edo State, 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