{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:47:34Z","timestamp":1788295654383,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To apply massage therapy accompanied with stretching exercises for treatment of mammary gland hyperplasia, evaluate the clinical outcome in patients, and estimate the therapy as a novel treatment method for mammary hyperplasia.<jats:italic>Methods<\/jats:italic>. 28 adult female patients were selected and treated with massage therapy and stretching exercises focusing on skeleton muscles of chest, abdomen, and axilla. The mammary gland oxyhemoglobin (OxyHb) and deoxyhemoglobin (DeoxyHb) levels were detected before and after treatment after 15, 30, and 45 days.<jats:italic>Results<\/jats:italic>. In this cohort, pretreatment OxyHb (mean \u00b1 SD) is<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">1.32<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.14<\/mml:mn><\/mml:math>(medium-high), and DeoxyHb is<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">0.87<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.13<\/mml:mn><\/mml:math>(normal). All patients were clinically diagnosed with benign mammary gland hyperplasia and mastitis. The posttreatment OxyHb levels are<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn fontstyle=\"italic\">1.23<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.09<\/mml:mn><\/mml:math>(normal-medium, 15-day),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn fontstyle=\"italic\">1.16<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.08<\/mml:mn><\/mml:math>(normal, 30-day), and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn fontstyle=\"italic\">1.05<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.04<\/mml:mn><\/mml:math>(normal, 45-day), and DeoxyHb levels are<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mn fontstyle=\"italic\">0.90<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.11<\/mml:mn><\/mml:math>(normal, 15-day),<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mn fontstyle=\"italic\">0.94<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.18<\/mml:mn><\/mml:math>(normal, 30-day), and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mn fontstyle=\"italic\">0.98<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.12<\/mml:mn><\/mml:math>(normal, 45-day). Patients were diagnosed with decreased hyperplasia 15 and 30 days after treatment and with no symptom of hyperplasia in mammary gland 45 days after treatment.<jats:italic>Conclusion<\/jats:italic>. Mammary gland hyperplasia is closely correlated with pathological changes of skeletal muscles and could be significantly improved by massage therapy and stretching exercises targeting neighboring skeletal muscles.<\/jats:p>","DOI":"10.1155\/2016\/9426167","type":"journal-article","created":{"date-parts":[[2016,2,28]],"date-time":"2016-02-28T16:01:22Z","timestamp":1456675282000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["A Study of Using Massage Therapy Accompanied with Stretching Exercise for Rehabilitation of Mammary Gland Hyperplasia"],"prefix":"10.1155","volume":"2016","author":[{"given":"Pin","family":"Lv","sequence":"first","affiliation":[{"name":"College of Physical Education, Anhui Normal University, Wuhu 241000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuping","family":"Chong","sequence":"additional","affiliation":[{"name":"College of Physical Education, Anhui Normal University, Wuhu 241000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huagang","family":"Zou","sequence":"additional","affiliation":[{"name":"College of Physical Education, Anhui Normal University, Wuhu 241000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7768-7240","authenticated-orcid":true,"given":"Xiangxian","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Physical Education, Anhui Normal University, Wuhu 241000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"20","key":"1","first-page":"3070","volume":"19","year":"2012","journal-title":"Chinese Journal of Primary Medicine and Pharmacy"},{"issue":"10","key":"2","first-page":"658","volume":"22","year":"2014","journal-title":"Chinese Journal of Family Planning"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2013.09.003"},{"key":"4","first-page":"S5","volume":"19","year":"2014","journal-title":"Journal of Research in Medical Sciences"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12110"},{"issue":"9","key":"6","first-page":"104","volume":"3","year":"2011","journal-title":"Journal of China Traditional Chinese Medicine Information"},{"issue":"1","key":"7","first-page":"122","volume":"35","year":"2014","journal-title":"Sichuan Medical Journal"},{"issue":"11","key":"8","first-page":"994","volume":"27","year":"2010","journal-title":"Practical Journal of Medicine & Pharmacy"},{"issue":"2","key":"9","first-page":"102","volume":"80","year":"1991","journal-title":"Annales Chirurgiae et Gynaecologiae"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620x.82b1.8954"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199411103311907"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/689012"},{"key":"13","year":"1982"},{"key":"14","year":"2011"},{"issue":"11","key":"15","first-page":"829","volume":"34","year":"2012","journal-title":"Chinese Journal of Physical Medicine and Rehabilitation"},{"key":"16","year":"2006"},{"key":"17","year":"2008"},{"key":"18","year":"2009"},{"issue":"5","key":"19","first-page":"65","volume":"32","year":"2009","journal-title":"Journal of Beijing Sport University"},{"key":"20","year":"2011"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/9426167.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/9426167.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/9426167.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T13:02:14Z","timestamp":1469538134000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2016\/9426167\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":20,"alternative-id":["9426167","9426167"],"URL":"https:\/\/doi.org\/10.1155\/2016\/9426167","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}