{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:11:59Z","timestamp":1792253519366,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002977","name":"Dalhousie University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002977","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Patients with hematologic malignancy (HM) often require intensive care unit (ICU) admission due to organ failure through disease progression or treatment-related complications.<jats:italic>Objective<\/jats:italic>. To determine mortality and prognostic variables in adult patients with HM who were admitted to ICU.<jats:italic>Methods<\/jats:italic>. Structured chart review of all adult patients (age \u2265 18 years) with HM admitted to ICU of a Canadian tertiary care hospital between 2004 and 2014. Outcome measures included mortality (ICU, 30-day, 60-day, and 12-month). Logistic regression was performed to determine predictors of mortality.<jats:italic>Results<\/jats:italic>. Overall, there were 206 cases of HM admitted to the ICU during the study (mean age: 51.3 \u00b1 13.6 years; 60% male). Median stay was 3 days, with 14.1% requiring prolonged ICU admission. ICU mortality was 45.6% and increased to 59.2% at 30 days, 62.6% at 60 days, and 74.3% at 12 months. Predictors of increased ICU mortality included mechanical ventilation requirement and vasopressor therapy requirement, while admission to ICU postoperatively and having myeloma were associated with decreased mortality.<jats:italic>Conclusions<\/jats:italic>. Patients admitted to ICU with HM have high mortality (45.6%), which increased to 74.3% at 1 year. Analysis of multiple variables identified critical illness, postsurgical admission, and myeloma as predictors of patient outcomes.<\/jats:p>","DOI":"10.1155\/2016\/9431385","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T04:08:57Z","timestamp":1458014937000},"page":"1-7","source":"Crossref","is-referenced-by-count":20,"title":["Predictors of Poor Outcomes in Critically Ill Adults with Hematologic Malignancy"],"prefix":"10.1155","volume":"2016","author":[{"given":"Marion","family":"Cornish","sequence":"first","affiliation":[{"name":"Department of Critical Care, Dalhousie University, Halifax, NS, Canada B3H 2Y9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Butler","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Dalhousie University, Halifax, NS, Canada B3H 2Y9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Dalhousie University, Halifax, NS, Canada B3H 2Y9"},{"name":"Trauma Nova Scotia, Halifax, NS, Canada B3H 2Y9"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/bf01706352"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12294"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-013-1675-7"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2015.04.002"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2009.10.002"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aer449"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1179\/1607845413y.0000000130"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-007-0268-1"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200210000-00014"},{"key":"10","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/175114370800900208","volume":"9","year":"2008","journal-title":"Journal of the Intensive Care Society"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200301000-00017"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2012.47.2365"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-10-516"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.031583"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2791-x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2005.10.020"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2594-0"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2010.11.003"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2012.07.014"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2014.01.014"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1179\/1607845412y.0000000038"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2010.255"},{"issue":"5","key":"23","first-page":"501","volume":"12","year":"1993","journal-title":"Bone Marrow Transplantation"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1186\/cc6923"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1179\/1607845414y.0000000206"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2010.07.006"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/917294"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2013.12.014"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/704318"}],"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9431385.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9431385.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9431385.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T04:19:59Z","timestamp":1498277999000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crj\/2016\/9431385\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":29,"alternative-id":["9431385","9431385"],"URL":"https:\/\/doi.org\/10.1155\/2016\/9431385","relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"value":"1198-2241","type":"print"},{"value":"1916-7245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}