{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T06:39:19Z","timestamp":1770446359028,"version":"3.49.0"},"reference-count":3,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>We present a case of a 15-month-old boy with Cornelia de Lange Syndrome (NIPBL gene mutation). On a PSG, central sleep apnea (central apnea-hypopnea index of 19\/hour) and nocturnal hypoventilation (transcutaneous CO<jats:sub>2<\/jats:sub>&gt; 50\u2009mmHg for 53% of the night) were found. A positive pressure initiation study was aborted because the patient developed a serious adverse reaction. The differential diagnosis included a skin fragility condition versus an allergic contact dermatitis to the interface; this could be from the povidone-iodine solution used to clean the NiPPV interface or from the plastic of the interface itself. A skin biopsy was performed which was normal. The reaction was likely secondary to an allergic contact dermatitis from the povidone-iodine solution used to clean the NiPPV interface. The patient is currently tolerating NiPPV.<\/jats:p>","DOI":"10.1155\/2016\/9712579","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T22:47:46Z","timestamp":1459291666000},"page":"1-2","source":"Crossref","is-referenced-by-count":6,"title":["An Adverse Reaction in the Pediatric Sleep Laboratory"],"prefix":"10.1155","volume":"2016","author":[{"given":"Diana","family":"Reppucci","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada M5G IX8"},{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra","family":"Medin","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada M5G IX8"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhail","family":"Al-Saleh","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada M5G IX8"},{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Jane","family":"Smith","sequence":"additional","affiliation":[{"name":"Janeway Children\u2019s Health and Rehabilitation Centre, St. John\u2019s, NL, Canada A1B 3V6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Barter","sequence":"additional","affiliation":[{"name":"Janeway Children\u2019s Health and Rehabilitation Centre, St. John\u2019s, NL, Canada A1B 3V6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reshma","family":"Amin","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada M5G IX8"},{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"5, article 860","key":"1","volume":"20","year":"1989","journal-title":"Journal of the American Academy of Dermatology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb04795.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb04790.x"}],"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9712579.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9712579.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/9712579.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T03:51:29Z","timestamp":1471578689000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crj\/2016\/9712579\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":3,"alternative-id":["9712579","9712579"],"URL":"https:\/\/doi.org\/10.1155\/2016\/9712579","relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"value":"1198-2241","type":"print"},{"value":"1916-7245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}