{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T05:51:02Z","timestamp":1771653062661,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Pediatrics"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Mobius Syndrome is a rare disease defined by bilateral congenital 7th nerve palsy. We focus on reporting the prevalence of orthopedic disease in this population.<jats:italic>Methods<\/jats:italic>. Twenty-three individuals with Mobius Syndrome underwent orthopedic physical examination, and additional 96 patients filled out a survey for self-reported orthopedic diagnoses.<jats:italic>Results<\/jats:italic>. Clubfoot was present in 60% of individuals in the physical exam series and 42% of those in the survey. Scoliosis was present in 26% and 28%, respectively. Poland\u2019s Syndrome was present in 17% and 30%. In addition to these findings, 27% of patients reported having difficulty with anesthesia, including difficulty in intubation and airway problems.<jats:italic>Conclusion<\/jats:italic>. An increased prevalence of scoliosis, clubfoot, transverse limb deficiencies, and Poland\u2019s Syndrome is identified in the setting of Mobius Syndrome. In the setting of several deformities often requiring surgical correction, a high incidence of anesthetic difficulty is noted and should be discussed with patients and other providers during surgical planning.<\/jats:p>","DOI":"10.1155\/2016\/9736723","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T21:01:18Z","timestamp":1454965278000},"page":"1-6","source":"Crossref","is-referenced-by-count":12,"title":["Orthopedic Manifestations of Mobius Syndrome: Case Series and Survey Study"],"prefix":"10.1155","volume":"2016","author":[{"given":"Philip","family":"McClure","sequence":"first","affiliation":[{"name":"Warren Alpert Medical School, Brown University, Providence, RI 02905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Booy","sequence":"additional","affiliation":[{"name":"Warren Alpert Medical School, Brown University, Providence, RI 02905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Katarincic","sequence":"additional","affiliation":[{"name":"Pediatric Hand Surgery, Rhode Island Hospital, Providence, RI 02905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Eberson","sequence":"additional","affiliation":[{"name":"Division of Pediatric Orthopedics, Rhode Island Hospital, Providence, RI 02905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000076484.91275.cd"},{"key":"2","year":"2013"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.27.2.122"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.10.3.249"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1971.00480310059005"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20941"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/bf02722639"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2006.05.019"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2006.03.015"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2012.11.009"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320230405"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1096-8628(19991029)86:5<492::aid-ajmg17>3.0.co;2-e"},{"issue":"4","key":"13","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1399-0004.1981.tb01030.x","volume":"20","year":"1981","journal-title":"Clinical Genetics"},{"issue":"6","key":"14","first-page":"436","volume":"85","year":"1992","journal-title":"Acta Neurologica Scandinavica"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340410"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3109\/13816819309087618"},{"issue":"2","key":"17","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1399-0004.1997.tb02433.x","volume":"51","year":"1997","journal-title":"Clinical Genetics"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500190071011"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.28.6.413"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1086\/302539"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/5.9.1367"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8199"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199709010-00007"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199809040-00004"}],"container-title":["International Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2016\/9736723.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2016\/9736723.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2016\/9736723.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T07:17:51Z","timestamp":1718349471000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijpedi\/2016\/9736723\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":24,"alternative-id":["9736723","9736723"],"URL":"https:\/\/doi.org\/10.1155\/2016\/9736723","relation":{},"ISSN":["1687-9740","1687-9759"],"issn-type":[{"value":"1687-9740","type":"print"},{"value":"1687-9759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}