{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T04:55:00Z","timestamp":1774414500295,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Chairman of the University of Cincinnati Department of Ophthalmology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To introduce a clinical sign on spectral domain optical coherence tomography (SDOCT), which may indicate high risk for full-thickness macular hole formation after internal limiting membrane (ILM) peeling.<jats:italic>Methods<\/jats:italic>. The preoperative SDOCT images of two patients\u2014one with multilaminar hemorrhage from ruptured retinal artery macroaneurysm and one with serous retinal detachment and severe macular schisis from optic pit maculopathy\u2014who developed full-thickness macular hole (FTMH) after ILM peeling were evaluated retrospectively.<jats:italic>Results<\/jats:italic>. On the preoperative SDOCT images of both patients there was a thin bridge of tissue on either side of the foveal center with an outer retinal defect. The photoreceptors were displaced laterally away from the foveal center to create an \u201c<jats:italic>omega-<\/jats:italic>\u201d shaped configuration of the remaining tissue.<jats:italic>Conclusion<\/jats:italic>. \u201c<jats:italic>Omega-<\/jats:italic>\u201d shaped configuration on SDOCT may represent a higher risk of FTMH following ILM peeling. Vitreoretinal surgeons may wish to consider this sign in the process of their surgical decision making.<\/jats:p>","DOI":"10.1155\/2016\/9858291","type":"journal-article","created":{"date-parts":[[2016,9,25]],"date-time":"2016-09-25T17:02:06Z","timestamp":1474822926000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Full-Thickness Macular Hole Formation after Internal Limiting Membrane Peeling: Beware the \u201c<i>Omega Sign<\/i>\u201d"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0328-7927","authenticated-orcid":true,"given":"Robert A.","family":"Sisk","sequence":"first","affiliation":[{"name":"Cincinnati Eye Institute, Cincinnati, OH, USA"},{"name":"Department of Ophthalmology, University of Cincinnati School of Medicine, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1072-3574","authenticated-orcid":true,"given":"Okan","family":"Toygar","sequence":"additional","affiliation":[{"name":"Cincinnati Eye Institute, Cincinnati, OH, USA"},{"name":"Department of Ophthalmology, Bahcesehir University Faculty of Medicine, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318227ab39"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.27.6.395.18189"},{"issue":"1","key":"3","first-page":"229","volume":"42","year":"2001","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.117.6.821"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.07.007"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-012-1983-y"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0B013E31824D0A4B"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.04.013"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000123"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/9858291.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/9858291.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2016\/9858291.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,9,25]],"date-time":"2016-09-25T17:02:08Z","timestamp":1474822928000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2016\/9858291\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":9,"alternative-id":["9858291","9858291"],"URL":"https:\/\/doi.org\/10.1155\/2016\/9858291","relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"value":"2090-6722","type":"print"},{"value":"2090-6730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}