{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:18Z","timestamp":1740164598423,"version":"3.37.3"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Richter\u2019s syndrome is the development of high-grade non-Hodgkin lymphoma (NHL) or Hodgkin lymphoma in patients with chronic lymphocytic leukemia (CLL)\/small lymphocytic lymphoma (SLL). In most patients with Richter\u2019s syndrome, the high-grade NHL is diffuse large B-cell lymphoma. Only a small minority of CLL\/SLL patients develop T-cell malignancies. Herein, we describe a 40-year-old male patient presenting with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) in the submandibular salivary gland, two years after the diagnosis of CLL\/SLL. The PTCL-NOS consisted of small lymphocytes, which complicated diagnosis. Immunohistochemical, cytological, and molecular studies allowed the correct diagnosis of composite lymphoma (SLL\/PTCL-NOS) of the submandibular salivary gland. The PTCL-NOS had a cytotoxic phenotype and aberrant expression of CD79a. There was no evidence to suggest that the PTCL-NOS of the submandibular salivary gland developed from an intimately associated submandibular lymph node or by PTCL-NOS dissemination. A review of the literature and presented case suppose that the PTCLs developed following CLL\/SLL have the cytotoxic phenotype and can clinically mimic typical Richter\u2019s syndrome.<\/jats:p>","DOI":"10.1155\/2017\/1262368","type":"journal-article","created":{"date-parts":[[2017,12,3]],"date-time":"2017-12-03T18:30:36Z","timestamp":1512325836000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Peripheral T-Cell Lymphoma of the Submandibular Salivary Gland as an Unusual Manifestation of Richter\u2019s Syndrome: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-1281","authenticated-orcid":true,"given":"Vadim R.","family":"Gorodetskiy","sequence":"first","affiliation":[{"name":"Department of Intensive Methods of Therapy, V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Kashirskoye shosse 34A, Moscow 115522, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalya A.","family":"Probatova","sequence":"additional","affiliation":[{"name":"Department of Pathology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Kashirskoye shosse 24, Moscow 115478, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0501-0326","authenticated-orcid":true,"given":"Tatiana T.","family":"Kondratieva","sequence":"additional","affiliation":[{"name":"Department of Pathology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Kashirskoye shosse 24, Moscow 115478, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20773"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1177\/1066896908324259"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(98)80122-2"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.2000.00294.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.7243\/2052-7896-3-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.04.023"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0b013e31826a5038"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200407000-00002"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2006.10.010"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124x.82272"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1177\/1066896912464047"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000140"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/98.4.424"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/103.3.348"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/108.3.316"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8652(200103)66:3<203::aid-ajh1045>3.0.co;2-x"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.1190"},{"year":"2008","key":"18"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880133"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880265"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0b013e32834c726f"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/183134"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197201)29:1<252::aid-cncr2820290138>3.0.co;2-#"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860801)58:3<699::aid-cncr2820580317>3.0.co;2-e"},{"year":"1991","key":"25"},{"year":"1994","key":"26"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1982.tb02763.x"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1990.tb00850.x"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1993.tb00077.x"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/s0046-8177(97)90113-1"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.8352"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.55.1.61"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1080\/10428190802702383"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2011.02747.x"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2005.03.6327"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/s0037-1963(03)00132-x"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.3109\/10428190009087022"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0320(20000615)42:3<188::aid-cyto5>3.0.co;2-q"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12067"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2013.802313"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3665"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2017\/1262368.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2017\/1262368.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2017\/1262368.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,3]],"date-time":"2017-12-03T18:30:36Z","timestamp":1512325836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crihem\/2017\/1262368\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":41,"alternative-id":["1262368","1262368"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1262368","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"type":"print","value":"2090-6560"},{"type":"electronic","value":"2090-6579"}],"subject":[],"published":{"date-parts":[[2017]]}}}