{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T19:19:09Z","timestamp":1775330349445,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T00:00:00Z","timestamp":1497312000000},"content-version":"vor","delay-in-days":163,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Ewing\u2019s sarcoma is a primary bone cancer that mainly affects the long bones. This malignancy is particularly common in pediatric patients. Primary cranial involvement accounts for 1% of cases, with occipital involvement considered extremely rare. In this case study, primary occipital Ewing\u2019s sarcoma with a posterior fossa mass and subsequent relapse resulting in spinal seeding is reported. A 3\u2010year\u2010old patient presented with a 1\u2010year history of left\u2010sided headaches, localized over the occipital bone with progressive torticollis. Computed tomography (CT) imaging showed a mass in the left posterior fossa compressing the brainstem. The patient then underwent surgical excision followed by adjuvant chemoradiation therapy. Two years later, the patient presented with severe lower back pain and urinary incontinence. Whole\u2010spine magnetic resonance imaging (MRI) showed cerebrospinal fluid (CSF) seeding from the L5 to the S4 vertebrae. Primary cranial Ewing\u2019s sarcoma is considered in the differential diagnosis of children with extra\u2010axial posterior fossa mass associated with destructive permeative bone lesions. Although primary cranial Ewing\u2019s sarcoma typically has good prognosis, our patient developed metastasis in the lower spine. Therefore, with CNS Ewing\u2019s sarcoma, screening of the entire neural axis should be taken into consideration for early detection of CSF seeding metastasis in order to decrease the associated morbidity and mortality.<\/jats:p>","DOI":"10.1155\/2017\/1521407","type":"journal-article","created":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T17:02:16Z","timestamp":1497373336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary Occipital Ewing\u2019s Sarcoma with Subsequent Spinal Seeding"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5493-2079","authenticated-orcid":false,"given":"Ali","family":"Alqahtani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4716-5342","authenticated-orcid":false,"given":"Roaa","family":"Amer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Bakhsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,13]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.4103\/0971-3026.29015"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198607000-00016"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/neurosurgery\/46.1.62"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31816e22f3"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197402)33:2<384::AID-CNCR2820330213>3.0.CO;2-T"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1246224"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-013-2255-9"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3203"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-872511"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.3.2243968"},{"key":"e_1_2_6_11_2","first-page":"2205","article-title":"Primary sclerosing rhabdomyosarcoma of the scalp and skull: Report of a case and review of literature","volume":"8","author":"Chen Q.","year":"2015","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050399"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5413.69304"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.136663"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2017\/1521407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2017\/1521407.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2017\/1521407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T23:53:21Z","timestamp":1762473201000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/1521407"}},"subtitle":[],"editor":[{"given":"Maria","family":"Moschovi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1155\/2017\/1521407"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1521407","archive":["Portico"],"relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1521407"}}