{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:33:48Z","timestamp":1740155628336,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Treatment of pelvic neoplasms with radiotherapy may develop sequelae, especially RHC. An 85-year-old male patient was admitted to a hospital emergency with gross hematuria leading to urinary retention and was diagnosed with RHC. The urinary bladder was probed, unobstructed, and maintained in continuous three-way saline irrigation. During 45 days of hospitalization, the patient underwent two cystoscopic procedures for urinary bladder flocculation, whole blood transfusions, and one platelet apheresis. None of these interventions led to clinical resolution. As the patient hematological condition was deteriorating, dexamethasone (4\u2009mg i.v.,<jats:italic> bolus<\/jats:italic> of 6\/6, 12\/12, and 24\u2009h during five days) and epoetin alpha (1000\u2009IU, 1\u2009ml, s.c., for four weeks) were administered which led to the remission of the urinary bleeding. Dexamethasone therapy may be considered for RHC, when conventional treatments are not effective or are not possible, avoiding more aggressive interventions such as cystectomy.<\/jats:p>","DOI":"10.1155\/2017\/1560363","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T17:02:30Z","timestamp":1498064550000},"page":"1-3","source":"Crossref","is-referenced-by-count":6,"title":["Treatment of Severe Refractory Hematuria due to Radiation-Induced Hemorrhagic Cystitis with Dexamethasone"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1490-2393","authenticated-orcid":true,"given":"Jos\u00e9 Carlos Rodrigues","family":"Nascimento","sequence":"first","affiliation":[{"name":"Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Wilker Soares","family":"Campelo","sequence":"additional","affiliation":[{"name":"Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iuri Arruda","family":"Arag\u00e3o","sequence":"additional","affiliation":[{"name":"Unimed Regional Hospital, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Fernando Bastos de","family":"Moura","sequence":"additional","affiliation":[{"name":"Cancer Institute of Ceara, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00facio Fl\u00e1vio Gonzaga","family":"Silva","sequence":"additional","affiliation":[{"name":"Cancer Institute of Ceara, Fortaleza, CE, Brazil"},{"name":"Department of Clinical Medicine, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinaldo Barreto","family":"Ori\u00e1","sequence":"additional","affiliation":[{"name":"Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Department of Morphology and Institute of Biomedicine, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2015.08.019"},{"issue":"2","key":"2","first-page":"57","volume":"18","year":"2016","journal-title":"Reviews Urology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/346812"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.12.056"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-5538.IBJU.2014.0411"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(95)91620-2"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(97)00248-9"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-015-0443-5"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.5980\/jpnjurol.102.600"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-2042.2003.00709.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/imj.12447"},{"issue":"5","key":"12","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1016\/S0022-5347(05)65134-8","volume":"167","year":"2002","journal-title":"The Journal of Urology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-11-318543"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2017\/1560363.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2017\/1560363.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2017\/1560363.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T17:02:35Z","timestamp":1498064555000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crim\/2017\/1560363\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":13,"alternative-id":["1560363","1560363"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1560363","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"type":"print","value":"1687-9627"},{"type":"electronic","value":"1687-9635"}],"subject":[],"published":{"date-parts":[[2017]]}}}