{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T01:43:37Z","timestamp":1783820617302,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To determine the contribution of drug use during pregnancy to the route of delivery.<jats:italic>Methods<\/jats:italic>. A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">236<\/mml:mn><\/mml:math>) were compared with a control group of low risk women (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">228<\/mml:mn><\/mml:math>) in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.).<jats:italic>p<\/jats:italic>values &lt; 0.05 were considered statistically significant.<jats:italic>Results<\/jats:italic>. Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.006<\/mml:mn><\/mml:math>). After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.567<\/mml:mn><\/mml:math>; 95% CI = 0.328\u20130.980). Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.008<\/mml:mn><\/mml:math>and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>, resp.) and fetal presentation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>), but not with the type of drug, route of administration, or substitution maintenance therapy.<jats:italic>Conclusions<\/jats:italic>. The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.<\/jats:p>","DOI":"10.1155\/2017\/1630967","type":"journal-article","created":{"date-parts":[[2017,2,26]],"date-time":"2017-02-26T16:00:41Z","timestamp":1488124841000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3417-5736","authenticated-orcid":true,"given":"Ana Raquel","family":"Neves","sequence":"first","affiliation":[{"name":"Department of Obstetrics B, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiane","family":"Neves","sequence":"additional","affiliation":[{"name":"Department of Obstetrics B, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Santos Silva","sequence":"additional","affiliation":[{"name":"Department of Obstetrics B, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria do C\u00e9u","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics B, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pitorra","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Department of Obstetrics B, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","series-title":"NSDUH Ser H-48, HHS Publ No 14-4863","year":"2014"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3931"},{"issue":"5","key":"3","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/AOG.0b013e318256496e","volume":"119","year":"2012","journal-title":"Obstetrics & Gynecology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2012.03.008"},{"issue":"4","key":"5","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1701-2163(16)34855-1","volume":"33","year":"2011","journal-title":"Journal of Obstetrics and Gynaecology Canada"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1018821"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2013.01.011"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.07.013"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2012.09.045"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/BF02849906"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70551-4"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-5576(99)00008-8"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2014.02.001"}],"container-title":["Journal of Pregnancy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2017\/1630967.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2017\/1630967.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2017\/1630967.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T07:24:36Z","timestamp":1498375476000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jp\/2017\/1630967\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":13,"alternative-id":["1630967","1630967"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1630967","relation":{},"ISSN":["2090-2727","2090-2735"],"issn-type":[{"value":"2090-2727","type":"print"},{"value":"2090-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}