{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:26:32Z","timestamp":1740147992467,"version":"3.37.3"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DO 637\/20-1"],"award-info":[{"award-number":["DO 637\/20-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DO 637\/20-1"],"award-info":[{"award-number":["DO 637\/20-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Karlsruhe Institute of Technology","award":["DO 637\/20-1"],"award-info":[{"award-number":["DO 637\/20-1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Radiofrequency ablation has become a first-line approach for curative therapy of many cardiac arrhythmias. Various existing catheter designs provide high spatial resolution to identify the best spot for performing ablation and to assess lesion formation. However, creation of transmural and nonconducting ablation lesions requires usage of catheters with larger electrodes and improved thermal conductivity, leading to reduced spatial sensitivity. As trade-off, an ablation catheter with integrated mini electrodes was introduced. The additional diagnostic benefit of this catheter is still not clear. In order to solve this issue, we implemented a computational setup with different ablation scenarios. Our<jats:italic>in silico<\/jats:italic>results show that peak-to-peak amplitudes of unipolar electrograms from mini electrodes are more suitable to differentiate ablated and nonablated tissue compared to electrograms from the distal ablation electrode. However, in orthogonal mapping position, no significant difference was observed between distal electrode and mini electrodes electrograms in the ablation scenarios. In conclusion, catheters with mini electrodes bring about additional benefit to distinguish ablated tissue from nonablated tissue in parallel position with high spatial resolution. It is feasible to detect conduction gaps in linear lesions with this catheter by evaluating electrogram data from mini electrodes.<\/jats:p>","DOI":"10.1155\/2017\/1686290","type":"journal-article","created":{"date-parts":[[2017,5,3]],"date-time":"2017-05-03T21:01:23Z","timestamp":1493845283000},"page":"1-13","source":"Crossref","is-referenced-by-count":7,"title":["Mini Electrodes on Ablation Catheters: Valuable Addition or Redundant Information?\u2014Insights from a Computational Study"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8254-2422","authenticated-orcid":true,"given":"Stefan","family":"Pollnow","sequence":"first","affiliation":[{"name":"Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-2962","authenticated-orcid":true,"given":"Joachim","family":"Greiner","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1495-4927","authenticated-orcid":true,"given":"Tobias","family":"Oesterlein","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany"}]},{"given":"Eike M.","family":"W\u00fclfers","sequence":"additional","affiliation":[{"name":"Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg, Bad Krozingen and Medical Faculty, University of Freiburg, Els\u00e4sser Str. 2Q, 79\u2009110 Freiburg im Breisgau, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2487-4744","authenticated-orcid":true,"given":"Axel","family":"Loewe","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany"}]},{"given":"Olaf","family":"D\u00f6ssel","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370090041008"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000185927.63746.23"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1994.tb01146.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.12.016"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.10.032"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.10.039"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0625-7"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01693.x"},{"key":"10","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4414\/cvm.2015.00313","volume":"18","year":"2015","journal-title":"Cardiovascular Medicine"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.06.014"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1161\/circep.113.000749"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.115.002476"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1611184114"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00388.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.678789"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.07.009"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2013.121"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12568"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12980"},{"key":"21","first-page":"363","volume":"15","year":"2010","journal-title":"Progress in Mathematics"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2011.0139"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2014.2322515"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00109.2006"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1515\/cdbme-2016-0134"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevBiomedEng.v38.i1.50"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1007\/bf02345754"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011477408021"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2010.05.008"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/41\/11\/003"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150356"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1186\/1475-925x-5-24"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1007\/bf02345754"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1114\/1.1310219"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1998.tb00108.x"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1995.tb00769.x"},{"key":"37","doi-asserted-by":"crossref","first-page":"599","DOI":"10.19102\/icrm.2012.030102","volume":"3","year":"2012","journal-title":"The Journal of Innovations in Cardiac Rhythm Management"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2017\/1686290.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2017\/1686290.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2017\/1686290.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T21:25:16Z","timestamp":1589750716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2017\/1686290\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":37,"alternative-id":["1686290","1686290"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1686290","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"type":"print","value":"1748-670X"},{"type":"electronic","value":"1748-6718"}],"subject":[],"published":{"date-parts":[[2017]]}}}