{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:07:40Z","timestamp":1790726860770,"version":"4.1.0"},"reference-count":193,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2016R1A5A2007009"],"award-info":[{"award-number":["2016R1A5A2007009"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>To date, three main gasotransmitters, that is, hydrogen sulfide (H<jats:sub>2<\/jats:sub>S), carbon monoxide (CO), and nitric oxide (NO), have been discovered to play major bodily physiological roles. These gasotransmitters have multiple functional roles in the body including physiologic and pathologic functions with respect to the cellular or tissue quantities of these gases. Gasotransmitters were originally known to have only detrimental and noxious effects in the body but that notion has much changed with years; vast studies demonstrated that these gasotransmitters are precisely involved in the normal physiological functioning of the body. From neuromodulation, oxidative stress subjugation, and cardiovascular tone regulation to immunomodulation, these gases perform critical roles, which, should they deviate from the norm, can trigger the genesis of a number of neurodegenerative diseases such as Alzheimer\u2019s disease (AD) and Parkinson\u2019s disease (PD). The purpose of this review is to discuss at great length physical and chemical properties and physiological actions of H<jats:sub>2<\/jats:sub>S, NO, and CO as well as shedding light on recently researched molecular targets. We particularly put emphasis on the roles in neuronal inflammation and neurodegeneration and neuronal repair.<\/jats:p>","DOI":"10.1155\/2017\/1689341","type":"journal-article","created":{"date-parts":[[2017,3,12]],"date-time":"2017-03-12T21:00:52Z","timestamp":1489352452000},"page":"1-15","source":"Crossref","is-referenced-by-count":59,"title":["Role of Gasotransmitters in Oxidative Stresses, Neuroinflammation, and Neuronal Repair"],"prefix":"10.1155","volume":"2017","author":[{"given":"Ulfuara","family":"Shefa","sequence":"first","affiliation":[{"name":"Department of Biomedical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8021-1024","authenticated-orcid":true,"given":"Seung Geun","family":"Yeo","sequence":"additional","affiliation":[{"name":"East-West Medical Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"},{"name":"Department of Otorhinolaryngology, H & N Surgery, College of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Sik","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Applied Chemistry, College of Applied Science, Kyung Hee University, Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Ok","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Reproductive Endocrinology and Infertility and Department of Obstetrics and Gynecology, Cheil General Hospital, Dankook University College of Medicine, 17 Seoae-ro 1 Gil, Jung-gu, Seoul 04619, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3946-5406","authenticated-orcid":true,"given":"Junyang","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"},{"name":"East-West Medical Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"},{"name":"Department of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2130-4719","authenticated-orcid":true,"given":"Na Young","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Cell Biology, College of Medicine, Dong-A University, 32 Daesingongwon-ro, Seo-gu, Busan 49201, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7687-0374","authenticated-orcid":true,"given":"Youngbuhm","family":"Huh","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"},{"name":"Department of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1089\/152308603768295249"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12483"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(99)00060-X"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06580.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.11.026"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/s0074-7742(07)82016-2"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9049782"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2004.03.021"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2005.12.006"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2006"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2005.06.001"},{"issue":"4-5","key":"12","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1159\/000094160","volume":"28","year":"2006","journal-title":"Developmental Neuroscience"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2010-1303"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2009.08.007"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1306.007"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/288373a0"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0211hyp"},{"key":"18","first-page":"3","volume-title":"The evolution of gasotransmitter biology and medicine","year":"2004"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/BF02255914"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1038\/nature12722"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706458"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.24.9265"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00183"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.44.101802.121844"},{"issue":"13","key":"25","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1096\/fasebj.7.13.8405815","volume":"7","year":"1993","journal-title":"FASEB Journal"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.74.6.1133"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1179\/016164104225016236"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.7.1039"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.30.2.252"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199908000-00028"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1007\/BF00294173"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1007\/BF00692225"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-0173(00)00043-6"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440716"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/s0960-8524(01)00029-3"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00722.2006"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.03.049"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.2174\/138920112800399086"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/S1367-5931(00)00193-9"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1428"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1021\/pr400617m"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402663111"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2014.137"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2011.96"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-012-1071-9"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-008-9904-5"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.03.002"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5667"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1021\/jp2061877"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1007\/s00775-002-0405-8"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1021\/ja204549n"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201200176"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029514"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2004.6.878"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1124\/pr.57.4.3"},{"issue":"6","key":"57","first-page":"L1029","volume":"279","year":"2000","journal-title":"American Journal of Physiology"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1016\/s1471-4906(03)00181-9"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1006\/bmme.1997.2610"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5674"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.13"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.2174\/1389450111009011517"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.46.120604.141046"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.2174\/1570162x12666140526122709"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.2174\/138945013804806433"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31822f0d64"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.607101"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041982"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-009-9014-4"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1186\/2045-9912-2-32"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2008.02.002"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2011"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1126\/science.1162667"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1308487110"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2012.10.019"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1097\/mnh.0000000000000096"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.90566.2008"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2007.05.016"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034562"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.240242"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.4805"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-014-0151-1"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.4948"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf077"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000042"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.06.030"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.06.002"},{"issue":"24","key":"92","doi-asserted-by":"crossref","first-page":"14143","DOI":"10.1016\/S0021-9258(18)77279-7","volume":"265","year":"1990","journal-title":"Journal of Biological Chemistry"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(91)91390-X"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1126\/science.1948068"},{"issue":"1","key":"95","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1523\/JNEUROSCI.19-01-00064.1999","volume":"19","year":"1999","journal-title":"Journal of Neuroscience"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1089\/089771501300227323"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9899.1000157"},{"issue":"3","key":"99","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1046\/j.1471-4159.1995.65031399.x","volume":"65","year":"1995","journal-title":"Journal of Neurochemistry"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)00125-2"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.6.1297"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1997.6752"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2015.08.007"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-010-9180-4"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-010-9477-z"},{"issue":"5","key":"106","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1046\/j.1471-4159.2001.00178.x","volume":"76","year":"2001","journal-title":"Journal of Neurochemistry"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2919"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2009.00543.x"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2008.2132"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.05.048"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1815fje"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1834314100"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2000464"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2010.05.016"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2926"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.05.002"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1096\/fj.05-4712fje"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00506.2012"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S65815"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)70016-5"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721080-00005"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23504"},{"key":"123","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26526"},{"key":"124","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-009-0006-9"},{"key":"125","first-page":"193","volume-title":"Brain, learning, and memory: role of H2S in neurodegenerative diseases","year":"2015"},{"key":"126","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5321.2045"},{"issue":"1, article no. 123","key":"127","volume":"68","year":"2000","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2003.08.008"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.10.5774"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.44.3_part_1.437"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-5769(01)00088-1"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2007.00065.x"},{"key":"133","doi-asserted-by":"publisher","DOI":"10.2174\/1381612023396375"},{"key":"134","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2006.04244.x"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(93)81706-6"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1098-2396(199605)23:1<58::aid-syn7>3.0.co;2-g"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-0618(98)00032-5"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2007.04528.x"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1249"},{"key":"140","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10722"},{"key":"141","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/297357"},{"key":"142","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-008-1200-1"},{"key":"143","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-014-0196-1"},{"key":"144","doi-asserted-by":"publisher","DOI":"10.2174\/156720509789207985"},{"key":"145","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(02)00780-3"},{"key":"146","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(96)00729-9"},{"key":"147","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-010-0436-1"},{"key":"148","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-012-0670-y"},{"key":"149","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.3649-04.2004"},{"key":"150","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.187260"},{"key":"151","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2012.06.021"},{"key":"152","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12729"},{"key":"153","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/432318"},{"key":"154","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011613"},{"key":"155","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2010.07.2039"},{"key":"156","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01215-12"},{"key":"157","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1203285"},{"key":"158","year":"2013"},{"key":"159","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2007.356"},{"key":"160","doi-asserted-by":"publisher","DOI":"10.1007\/BF00588024"},{"key":"161","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(02)00422-9"},{"key":"162","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.4612"},{"key":"163","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-015-9212-4"},{"key":"164","doi-asserted-by":"publisher","DOI":"10.3109\/13685538.2012.668722"},{"key":"165","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0170tr"},{"key":"166","doi-asserted-by":"publisher","DOI":"10.1016\/s0070-2137(01)80008-x"},{"key":"167","doi-asserted-by":"publisher","DOI":"10.1016\/0169-328X(94)00273-H"},{"issue":"4","key":"168","first-page":"871","volume":"152","year":"1998","journal-title":"American Journal of Pathology"},{"key":"169","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06007.x"},{"key":"170","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2011-102061"},{"key":"171","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2012.07914.x"},{"key":"172","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2004.09.015"},{"key":"173","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145711001118"},{"key":"174","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.03.020"},{"key":"175","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.529"},{"key":"176","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410370609"},{"key":"177","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2010.04.004"},{"key":"178","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5849(02)01327-8"},{"key":"179","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-0173(00)00051-5"},{"key":"180","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.10.5795"},{"key":"181","doi-asserted-by":"publisher","DOI":"10.4236\/jbm.2014.27001"},{"key":"182","doi-asserted-by":"publisher","DOI":"10.1002\/glia.440070113"},{"issue":"4","key":"183","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1523\/JNEUROSCI.21-04-01179.2001","volume":"21","year":"2001","journal-title":"Journal of Neuroscience"},{"key":"184","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.1197"},{"key":"185","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.4.1425"},{"key":"186","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.07.008"},{"key":"187","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02455.x"},{"key":"188","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000536"},{"key":"189","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0482-06.2006"},{"key":"190","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-132928"},{"key":"191","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0902714106"},{"issue":"2","key":"192","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3233\/JAD-2008-14210","volume":"14","year":"2008","journal-title":"Journal of Alzheimer's Disease"},{"key":"193","first-page":"597","volume":"5","year":"2009","journal-title":"Neuropsychiatric Disease and Treatment"},{"key":"194","doi-asserted-by":"publisher","DOI":"10.2174\/138161210793176572"},{"issue":"21","key":"195","doi-asserted-by":"crossref","first-page":"8370","DOI":"10.1523\/JNEUROSCI.21-21-08370.2001","volume":"21","year":"2001","journal-title":"Journal of Neuroscience"},{"key":"196","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2010.01.040"},{"key":"197","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.6.3034"},{"key":"198","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2010.11.034"},{"key":"199","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/467180"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/1689341.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/1689341.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/1689341.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T23:07:27Z","timestamp":1719097647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2017\/1689341\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":193,"alternative-id":["1689341","1689341"],"URL":"https:\/\/doi.org\/10.1155\/2017\/1689341","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}