{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T21:10:31Z","timestamp":1757452231149,"version":"3.37.3"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Education, Australia","award":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"],"award-info":[{"award-number":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"]}]},{"name":"Carlos III Institute of Health","award":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"],"award-info":[{"award-number":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"]}]},{"name":"Carlos III Institute of Health","award":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"],"award-info":[{"award-number":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"]}]},{"name":"Carlos III Institute of Health","award":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"],"award-info":[{"award-number":["SB2009-0175","TPY 1529\/07","TPY 1444\/08","ESPY 1281\/15"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. Understanding the presentation of spinal cord injury (SCI) due to tumours considering population distribution and temporal trends is key to managing SCI health services. This study quantified incidence rates, function scores, and trends of SCI due to tumour or metastasis over an 18-year time period in a defined region in Spain.<jats:italic> Methods<\/jats:italic>. A retrospective cohort study included in-and outpatients with nontraumatic SCI due to tumour or metastasis admitted to a metropolitan hospital in Spain between 1991 and 2008. Main outcome measures were crude and age- and sex-adjusted incidence rates, tumour location and type, distribution by spinal level, neurological level of injury, and impairment ASIA scores.<jats:italic> Results<\/jats:italic>. Primary tumour or metastasis accounted for 32.5% of nontraumatic SCI with an incidence rate of 4.1 per million population. Increasing rates with age and over time were observed. Major pathology groups were intradural-extramedullary masses from which meningiomas and neurinomas accounted for 40%. Lesions were mostly incomplete with predominant ASIA Grade D.<jats:italic> Conclusions<\/jats:italic>. Increasing incidence rates of tumour-related SCI over time in the middle-aged and the elderly suggest a growing need for neurooncology health resources in the future.<\/jats:p>","DOI":"10.1155\/2017\/2478197","type":"journal-article","created":{"date-parts":[[2017,7,25]],"date-time":"2017-07-25T17:02:02Z","timestamp":1501002122000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Spinal Cord Injury due to Tumour or Metastasis in Arag\u00f3n, Northeastern Spain (1991\u20132008): Incidence, Time Trends, and Neurological Function"],"prefix":"10.1155","volume":"2017","author":[{"given":"Maayken Elizabeth Louise","family":"van den Berg","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, Aged and Extended Care, Flinders University, Adelaide, SA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7242-8730","authenticated-orcid":true,"given":"Juan M.","family":"Castellote","sequence":"additional","affiliation":[{"name":"National School of Occupational Medicine, Carlos III Institute of Health, Madrid, Spain"},{"name":"Department of Physical Medicine and Rehabilitation, School of Medicine, Complutense University of Madrid, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Ignacio","family":"Mayordomo","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, University of Colorado Hospital, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Mahillo-Fernandez","sequence":"additional","affiliation":[{"name":"University Hospital Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Av. 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