{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:02:16Z","timestamp":1740164536599,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2017]]},"abstract":"Introduction<\/jats:italic>. Management of postoperative central diabetes insipidus (DI) can be challenging from changes in volume status and serum sodium levels. We report a case successfully using a dilute vasopressin bolus protocol in managing hypovolemic shock in acute, postoperative, central DI. Case Report<\/jats:italic>. Patient presented after bifrontal decompressive craniotomy for severe traumatic brain injury. He developed increased urine output resulting in hypovolemia and hypernatremia. He was resuscitated with intravenous fluids including a dilute vasopressin bolus protocol. This protocol consisted of 1 unit of vasopressin in 1 liter of 0.45% normal saline. This protocol was given in boluses based on the formula: urine output minus one hundred. Initial serum sodium was 148\u2009mmol\/L, and one-hour urine output was 1 liter. After 48 hours, he transitioned to 1-desamino-8-D-arginine vasopressin (DDAVP). Pre-DDAVP serum sodium was 149\u2009mmol\/L and one-hour urine output 320\u2009cc. Comparing the bolus protocol to the DDAVP protocol, the average sodium was 143.8 \u00b1 3.2 and 149.6 \u00b1 3.2\u2009mmol\/L (p<\/mml:mi>=<\/mml:mo>0.0001<\/mml:mn><\/mml:math>), average urine output was 433.2 \u00b1 354.4 and 422.3 \u00b1 276.0\u2009cc\/hr (p<\/mml:mi>=<\/mml:mo>0.90<\/mml:mn><\/mml:math>), and average specific gravity was 1.019 \u00b1 0.009 and 1.016 \u00b1 0.01 (p<\/mml:mi>=<\/mml:mo>0.42<\/mml:mn><\/mml:math>), respectively. Conclusion<\/jats:italic>. A protocol using dilute vasopressin bolus can be an alternative for managing acute, central DI postoperatively, particularly in setting of hypovolemic shock resulting in a consistent control of serum sodium.<\/jats:p>","DOI":"10.1155\/2017\/3052102","type":"journal-article","created":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T16:00:53Z","timestamp":1483459253000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Vasopressin Bolus Protocol Compared to Desmopressin (DDAVP) for Managing Acute, Postoperative Central Diabetes Insipidus and Hypovolemic Shock"],"prefix":"10.1155","volume":"2017","author":[{"given":"Anukrati","family":"Shukla","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syeda","family":"Alqadri","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Ausmus","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Premkumar","family":"Nattanmai","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-7791","authenticated-orcid":true,"given":"Christopher R.","family":"Newey","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Missouri, Columbia, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.12.FOCUS10235"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu263"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1159\/000336333"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/ndtplus\/sfp117"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9572(00)00196-9"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.8.896"},{"volume-title":"Disorders of the neurohypophysis","year":"2015","key":"7"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-73-5-721"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5876.375"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-46-3-381"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2017\/3052102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2017\/3052102.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2017\/3052102.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T16:00:53Z","timestamp":1483459253000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crie\/2017\/3052102\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":10,"alternative-id":["3052102","3052102"],"URL":"https:\/\/doi.org\/10.1155\/2017\/3052102","relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"type":"print","value":"2090-6501"},{"type":"electronic","value":"2090-651X"}],"subject":[],"published":{"date-parts":[[2017]]}}}