{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:07:14Z","timestamp":1740103634527,"version":"3.37.3"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"local government in Pr\u00edncipe Island"},{"name":"Ascendere Non-Governmental Organization, Portugal"},{"name":"Unilabs, Portugal"},{"name":"Femicare, Clinical Research for Women, a nonprofit organization in Belgium"},{"name":"AML, molecular biology lab in Belgium"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Pr\u00edncipe (S\u00e3o Tom\u00e9 and Pr\u00edncipe).<jats:italic> Methods<\/jats:italic>. Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount microscopy) and a cervical sample (ThinPrep\u00ae) (Pap test, high risk<jats:italic> human papillomavirus<\/jats:italic> [HR-HPV],<jats:italic> N<\/jats:italic>.<jats:italic> gonorrhea<\/jats:italic> [NG],<jats:italic> T<\/jats:italic>.<jats:italic> vaginalis<\/jats:italic> [TV], and<jats:italic> C<\/jats:italic>.<jats:italic> trachomatis<\/jats:italic> [CT]) were obtained.<jats:italic> Results<\/jats:italic>. TV, NG, CT, and HIV were found in 8.0%, 2.0%, 3.0%, and 2.0%, respectively, and were more prevalent in younger women. HR-HPV was positive in 36.7%; 2 were positive for HPV18, but none for HPV16. Coinfection of HPV with other STIs was 8.3%. Prevalence of abnormal vaginal flora (AVF) was 82.5%, mostly bacterial vaginosis (BV) 54.6%, and moderate\/severe aerobic vaginitis (msAV) 25.8%. HR-HPV was not related to BV (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.67<\/mml:mn><\/mml:math>). The association of abnormal Pap test with msAV was not significant (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.08<\/mml:mn><\/mml:math>).<jats:italic> Conclusion<\/jats:italic>. The prevalence of NG, CT, TV, and HR-HPV was according to expected, while that of HR-AVF was higher. The surprisingly low prevalence of HPV16 and HPV18 must be considered in the design of programs for prevention and vaccination; this setting can be useful as a model for postvaccination scenarios.<\/jats:p>","DOI":"10.1155\/2017\/3058569","type":"journal-article","created":{"date-parts":[[2017,11,13]],"date-time":"2017-11-13T18:31:01Z","timestamp":1510597861000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Genital Tract Infections in an Isolated Community: 100 Women of the Pr\u00edncipe Island"],"prefix":"10.1155","volume":"2017","author":[{"given":"Pedro","family":"Vieira-Baptista","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Centro Hospitalar de S\u00e3o Jo\u00e3o, Porto, Portugal"},{"name":"Ascendere Non-Governmental Organization, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svitrigaile","family":"Grinceviciene","sequence":"additional","affiliation":[{"name":"Femicare, Clinical 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