{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:49:52Z","timestamp":1785797392336,"version":"3.56.0"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"crossref","award":["FAPESP\u20132014\/13055-0"],"award-info":[{"award-number":["FAPESP\u20132014\/13055-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>A retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosion (EC), bone sclerosis focal (FS) and diffuse (DS), bone sequestration (BS), thickening of lamina dura (TD), prominence of the inferior alveolar nerve canal (IAN), persisting alveolar sockets (SK), and the presence of a pathological fracture (PF). Medical information and staging were also recorded in order to correlate with radiographic findings. Bone sclerosis was the most frequent alteration, followed by OT and TD. The mandible was more affected than the maxilla. There was no significant difference between genders or significant correlation between the number of injuries with age and duration of BP usage. Considering the association between the radiographic findings and MRONJ staging, EC was predominant in stage 3 and DS in stage 2. IAN and PF demonstrated greater association with stage 3. In conclusion, the higher the clinical staging, the greater the severity of the bone alteration. Panoramic radiographic examination is a useful screening tool in patients submitted to antiresorptive therapy.<\/jats:p>","DOI":"10.1155\/2017\/3190301","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T16:01:17Z","timestamp":1488470477000},"page":"1-6","source":"Crossref","is-referenced-by-count":42,"title":["Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9545-6809","authenticated-orcid":true,"given":"Camila Lopes","family":"Cardoso","sequence":"first","affiliation":[{"name":"Department of Oral Surgery, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Arrabal","family":"Barros","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e1udia","family":"Curra","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana Maria Paes da Silva Ramos","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Oral Radiology, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange de Oliveira Braga","family":"Franzolin","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel Santiago Ferreira","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos C\u00e9sar","family":"De Antoni","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Universidade do Sagrado Cora\u00e7\u00e3o, Bauru, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Martins","family":"Curi","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Hospital Santa Catarina, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.04.031"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.12.002"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/27458726"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.05.003"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2011.08.016"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2008.01494.x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/s0278-2391(03)00720-1"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-009-0293-1"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0518"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.04.033"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.02.009"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.02.012"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2012.01911.x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.06.004"}],"container-title":["International Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijd\/2017\/3190301.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijd\/2017\/3190301.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijd\/2017\/3190301.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T16:01:20Z","timestamp":1488470480000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ijd\/2017\/3190301\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":14,"alternative-id":["3190301","3190301"],"URL":"https:\/\/doi.org\/10.1155\/2017\/3190301","relation":{},"ISSN":["1687-8728","1687-8736"],"issn-type":[{"value":"1687-8728","type":"print"},{"value":"1687-8736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}