{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:17:30Z","timestamp":1790453850845,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG1E0021"],"award-info":[{"award-number":["CMRPG1E0021"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG1B0132"],"award-info":[{"award-number":["CMRPG1B0132"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["104-2314-B-182A-138"],"award-info":[{"award-number":["104-2314-B-182A-138"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["104-2410-H-038-006-SSS"],"award-info":[{"award-number":["104-2410-H-038-006-SSS"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["105-2410-H-038-011-SSS"],"award-info":[{"award-number":["105-2410-H-038-011-SSS"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG1E0021"],"award-info":[{"award-number":["CMRPG1E0021"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG1B0132"],"award-info":[{"award-number":["CMRPG1B0132"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["104-2314-B-182A-138"],"award-info":[{"award-number":["104-2314-B-182A-138"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["104-2410-H-038-006-SSS"],"award-info":[{"award-number":["104-2410-H-038-006-SSS"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["105-2410-H-038-011-SSS"],"award-info":[{"award-number":["105-2410-H-038-011-SSS"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1E0021"],"award-info":[{"award-number":["CMRPG1E0021"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1B0132"],"award-info":[{"award-number":["CMRPG1B0132"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2314-B-182A-138"],"award-info":[{"award-number":["104-2314-B-182A-138"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2410-H-038-006-SSS"],"award-info":[{"award-number":["104-2410-H-038-006-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["105-2410-H-038-011-SSS"],"award-info":[{"award-number":["105-2410-H-038-011-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1E0021"],"award-info":[{"award-number":["CMRPG1E0021"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1B0132"],"award-info":[{"award-number":["CMRPG1B0132"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2314-B-182A-138"],"award-info":[{"award-number":["104-2314-B-182A-138"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2410-H-038-006-SSS"],"award-info":[{"award-number":["104-2410-H-038-006-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["105-2410-H-038-011-SSS"],"award-info":[{"award-number":["105-2410-H-038-011-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1E0021"],"award-info":[{"award-number":["CMRPG1E0021"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["CMRPG1B0132"],"award-info":[{"award-number":["CMRPG1B0132"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2314-B-182A-138"],"award-info":[{"award-number":["104-2314-B-182A-138"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["104-2410-H-038-006-SSS"],"award-info":[{"award-number":["104-2410-H-038-006-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["105-2410-H-038-011-SSS"],"award-info":[{"award-number":["105-2410-H-038-011-SSS"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Infant holding position may reduce vaccination pain. However, the optimal position for young infants remains controversial.<jats:italic> Objectives<\/jats:italic>. To compare the effectiveness of holding infants in the supine position and the effectiveness of holding infants in upright position for relieving acute pain from vaccine injection.<jats:italic> Methods<\/jats:italic>. This prospective cohort study enrolled 6\u201312-week-old healthy infants. We examined infant pain responses by evaluating the following three categories: (1) crying, (2) irritability, and (3) facial expression.<jats:italic> Results<\/jats:italic>. In total, 282 infants were enrolled, with 103 and 179 held in the supine and upright positions, respectively. At 30\u2009s after vaccination, the infants in the supine position showed a larger decrease in crying (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>), irritability (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.002<\/mml:mn><\/mml:math>), and pained facial expression (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>) than did those in the upright position. However, there was no significant difference in pain response between two groups at 180\u2009s after intervention.<jats:italic> Conclusion<\/jats:italic>. In 2-month-old infants, the supine position may reduce acute pain more effectively than does the upright position. Our findings provide a clinical strategy for relieving vaccination pain in young infants.<\/jats:p>","DOI":"10.1155\/2017\/3273171","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T21:49:16Z","timestamp":1485467356000},"page":"1-7","source":"Crossref","is-referenced-by-count":7,"title":["Comparative Survey of Holding Positions for Reducing Vaccination Pain in Young Infants"],"prefix":"10.1155","volume":"2017","author":[{"given":"Hui-Chu","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Nursing, Chang Gung Memorial Hospital, College of Nursing, Chang Gung University, Taipei 105, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Wen","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taipei 105, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yuh","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kaohsiung Medical University, Kaohsiung 807, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Wen","family":"Chiu","sequence":"additional","affiliation":[{"name":"Master Program in Global Health and Development, College of Public Health, Taipei Medical University, Taipei 11031, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6955-8593","authenticated-orcid":true,"given":"Yi-Hao","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taipei 105, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-4102"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.04.037"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.08.104"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2015.09.002"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.150391"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.cd006275.pub3"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-14-134"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1107"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmn.2010.07.008"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/ajp.0000000000000281"},{"issue":"12","key":"11","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-3719"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.157.11.1115"},{"key":"14","volume":"10","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"39","key":"15","first-page":"505","volume":"90","year":"2015","journal-title":"Weekly Epidemiological Record"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3928\/0090-4481-19980601-12"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1607"},{"issue":"2","key":"18","first-page":"111","volume":"12","year":"2007","journal-title":"Paediatrics& Child Health"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318296079e"},{"issue":"1","key":"20","first-page":"49","volume":"15","year":"1999","journal-title":"Advances in Mind-Body Medicine"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3466"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/s0264-410x(00)00466-7"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162201000056"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2007.09.007"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.35"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2009.07.024"},{"issue":"1","key":"27","first-page":"e2","volume":"11","year":"2004","journal-title":"Canadian Journal of Clinical Pharmacology"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1097\/ajp.0000000000000103"},{"key":"29","volume":"10","year":"2013","journal-title":"The Cochrane Database of Systematic Reviews"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/232316"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1097\/00005237-200310000-00009"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20110196"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2007.04.010"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.09.019"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedhc.2012.02.009"}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2017\/3273171.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2017\/3273171.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2017\/3273171.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T14:27:51Z","timestamp":1589725671000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/prm\/2017\/3273171\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":35,"alternative-id":["3273171","3273171"],"URL":"https:\/\/doi.org\/10.1155\/2017\/3273171","relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}