{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:54:51Z","timestamp":1791255291274,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003970","name":"Isfahan University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003970","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. The current study is aimed at investigating the association between stressful life events and psychological problems in a large sample of Iranian adults.<jats:italic> Method<\/jats:italic>. In a cross-sectional large-scale community-based study, 4763 Iranian adults, living in Isfahan, Iran, were investigated. Grouped outcomes latent factor regression on latent predictors was used for modeling the association of psychological problems (depression, anxiety, and psychological distress), measured by Hospital Anxiety and Depression Scale (HADS) and General Health Questionnaire (GHQ-12), as the grouped outcomes, and stressful life events, measured by a self-administered stressful life events (SLEs) questionnaire, as the latent predictors.<jats:italic> Results<\/jats:italic>. The results showed that the personal stressors domain has significant positive association with psychological distress (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.19<\/mml:mn><\/mml:math>), anxiety (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.25<\/mml:mn><\/mml:math>), depression (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.15<\/mml:mn><\/mml:math>), and their collective profile score (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.20<\/mml:mn><\/mml:math>), with greater associations in females (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.28<\/mml:mn><\/mml:math>) than in males (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>\u03b2<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.13<\/mml:mn><\/mml:math>) (all <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>). In addition, in the adjusted models, the regression coefficients for the association of social stressors domain and psychological problems profile score were 0.37, 0.35, and 0.46 in total sample, males, and females, respectively (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>).<jats:italic> Conclusion<\/jats:italic>. Results of our study indicated that different stressors, particularly those socioeconomic related, have an effective impact on psychological problems. It is important to consider the social and cultural background of a population for managing the stressors as an effective approach for preventing and reducing the destructive burden of psychological problems.<\/jats:p>","DOI":"10.1155\/2017\/3457103","type":"journal-article","created":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T17:00:39Z","timestamp":1505840439000},"page":"1-12","source":"Crossref","is-referenced-by-count":60,"title":["Association of Stressful Life Events with Psychological Problems: A Large-Scale Community-Based Study Using Grouped Outcomes Latent Factor Regression with Latent Predictors"],"prefix":"10.1155","volume":"2017","author":[{"given":"Akbar","family":"Hassanzadeh","sequence":"first","affiliation":[{"name":"Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, 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