{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:32:40Z","timestamp":1787934760183,"version":"build-2784847793"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,5,7]],"date-time":"2017-05-07T00:00:00Z","timestamp":1494115200000},"content-version":"vor","delay-in-days":126,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Sevoflurane is rarely used for the treatment of status asthmaticus. We report a case of sevoflurane hepatotoxicity in pregnancy with presentation similar to HELLP syndrome. <jats:italic>Case<\/jats:italic>. A G2P1001 at 23 weeks in status asthmaticus presented with pCO2 &gt; 130 and pH &lt; 7. She was nonresponsive to traditional therapy. Sevoflurane was added for a 24\u2009hr period. Respiratory status improved. Extubation occurred on day 12. Workup for preeclampsia spectrum disorders occurred due to maternal hypertension. Given the atypical presentation and hepatotoxicity, a liver biopsy was performed. Histologic features suggested drug induced hepatic injury. Liver function subsequently normalized. She delivered a term neonate without short\u2010term complications. <jats:italic>Conclusion<\/jats:italic>. The use of sevoflurane is a treatment option of status asthmaticus during pregnancy. Providers should be aware of the potential for hepatotoxicity.<\/jats:p>","DOI":"10.1155\/2017\/3547242","type":"journal-article","created":{"date-parts":[[2017,5,7]],"date-time":"2017-05-07T17:00:37Z","timestamp":1494176437000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Case of Sevoflurane Use during Pregnancy in the Management of Persistent Status Asthmaticus"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3372-2072","authenticated-orcid":false,"given":"Jessica","family":"Parrott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitch","family":"Tener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Dennis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Sharpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0088-8578","authenticated-orcid":false,"given":"Cecily","family":"Clark-Ganheart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,5,7]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066608324295"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet257"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-0045-x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.03.017"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.897"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1563389"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000268512.26170.ad"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00822.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2003.00181.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.3.1140"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.20153"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2017\/3547242.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2017\/3547242.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2017\/3547242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T16:55:06Z","timestamp":1756054506000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/3547242"}},"subtitle":[],"editor":[{"given":"Svein","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1155\/2017\/3547242"],"URL":"https:\/\/doi.org\/10.1155\/2017\/3547242","archive":["Portico"],"relation":{},"ISSN":["2090-6684","2090-6692"],"issn-type":[{"value":"2090-6684","type":"print"},{"value":"2090-6692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3547242"}}