{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:35:38Z","timestamp":1777487738355,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fisher & Paykel Healthcare Ltd., Auckland, New Zealand"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sleep Disorders"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objectives\/Background<\/jats:italic>. Improving adherence to CPAP devices is crucial to reduce the long-term morbidity associated with OSA. SensAwake is a unique pressure relief technology that aims to promptly reduce the pressure upon sensing irregular respiration indicative of wakefulness. The purpose of this study was to compare adherence and sleep-quality outcomes in patients treated by CPAP with and without SensAwake technology.<jats:italic>Methods<\/jats:italic>. Participants with moderate-to-severe OSA were randomized to use CPAP devices with or without SensAwake (4 weeks) before crossing over.<jats:italic>Results<\/jats:italic>. Sixty-five patients completed both arms of the trial. There were no statistically significant differences in CPAP adherence with or without SensAwake over the study period (SensAwake ON<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">272.67<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">17.06<\/mml:mn><\/mml:math>versus SensAwake OFF<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">289.09<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">15.24<\/mml:mn><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.180<\/mml:mn><\/mml:math>). SensAwake reported a significantly lower system leak, 90th percentile leak, and time spent with excessive (&gt;60\u2009L\/min) leak. Subgroup analysis suggested a trend towards improved adherence in patients with moderate-to-severe insomnia when using SensAwake.<jats:italic>Conclusions<\/jats:italic>. Using SensAwake incurred benefit in terms of reduced leaks; however, SensAwake did not improve CPAP adherence or objective sleep quality. Further studies should investigate the accuracy of observed trends towards increased adherence using SensAwake among patients with OSA and insomnia.<\/jats:p>","DOI":"10.1155\/2017\/3978073","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T23:32:38Z","timestamp":1513726358000},"page":"1-6","source":"Crossref","is-referenced-by-count":13,"title":["A Randomized Crossover Trial of a Pressure Relief Technology (SensAwake\u2122) in Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7043-2974","authenticated-orcid":true,"given":"Richard K.","family":"Bogan","sequence":"first","affiliation":[{"name":"SleepMed of South Carolina, Columbia, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Wells","sequence":"additional","affiliation":[{"name":"SleepMed of Central Georgia, Macon, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(01)00072-7"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.03.003"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.3418"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0810"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1159\/000322838"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcp.0000245715.97256.32"},{"issue":"2","key":"9","first-page":"245","volume":"131","year":"2010","journal-title":"Indian Journal of Medical Research"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2011.01.003"},{"issue":"1","key":"11","first-page":"99","volume":"32","year":"2009","journal-title":"SLEEP"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(11)70267-2"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.5664\/JCSM.1066"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3166"},{"issue":"2","key":"15","doi-asserted-by":"crossref","first-page":"196","DOI":"10.5664\/jcsm.27772","volume":"6","year":"2010","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2010.03.012"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-012-0655-9"}],"container-title":["Sleep Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/sd\/2017\/3978073.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/sd\/2017\/3978073.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/sd\/2017\/3978073.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,24]],"date-time":"2020-10-24T14:43:51Z","timestamp":1603550631000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/sd\/2017\/3978073\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":17,"alternative-id":["3978073","3978073"],"URL":"https:\/\/doi.org\/10.1155\/2017\/3978073","relation":{},"ISSN":["2090-3545","2090-3553"],"issn-type":[{"value":"2090-3545","type":"print"},{"value":"2090-3553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}