{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:15:24Z","timestamp":1740165324168,"version":"3.37.3"},"reference-count":4,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Rheumatology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>This case report describes a patient with scleroderma who developed <jats:italic>Mycobacterium intracellulare<\/jats:italic> infection, which for more than a year mimicked worsening of her connective tissue disorder. The patient was diagnosed with scleroderma based on puffy fingers that developed into sclerodactyly, abnormal nail fold capillaries, interstitial lung disease, Raynaud\u2019s phenomenon, esophageal dysmotility, and positivity for rheumatoid factor and anti-SSA antibodies. She developed massive inflammatory changes of the cutis, the subcutis, and the muscle fasciae of the right leg, that after several failed attempts of immunosuppressive treatments were found to be caused by <jats:italic>Mycobacterium intracellulare<\/jats:italic>. While she was receiving high-dose prednisolone, as worsening of her connective tissue disease was suspected to be the cause of the inflammatory changes, she had <jats:italic>Listeria monocytogenes<\/jats:italic> meningitis and was hospitalized for several weeks, but she recovered from this without sequelae. After <jats:italic>Mycobacterium intracellulare<\/jats:italic> infection was diagnosed, she was treated with clarithromycin and rifampicin. Her skin manifestations, arthralgias, and fatigue improved considerably, and the wounds of the right leg healed, unfortunately with significant scarring. Immunodeficiency testing was unremarkable. In summary, an infection with <jats:italic>Mycobacterium intracellulare<\/jats:italic> was mistaken for an unusually severe progression of scleroderma.<\/jats:p>","DOI":"10.1155\/2017\/4029271","type":"journal-article","created":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T17:00:44Z","timestamp":1506531644000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["<i>Mycobacterium intracellulare<\/i> Infection Mimicking Progression of Scleroderma"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2877-1582","authenticated-orcid":true,"given":"Simon","family":"Krabbe","sequence":"first","affiliation":[{"name":"Center for Rheumatology and Spine Diseases, Rigshospitalet, 2600 Glostrup, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merete","family":"Engelhart","sequence":"additional","affiliation":[{"name":"Center for Rheumatology and Spine Diseases, Gentofte Hospital, 2900 Hellerup, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f6ren","family":"Thybo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Rigshospitalet, 2100 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Center for Rheumatology and Spine Diseases, Rigshospitalet, 2100 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204424"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2014.11.002"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2016.07.004"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12266"}],"container-title":["Case Reports in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2017\/4029271.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2017\/4029271.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2017\/4029271.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T17:00:44Z","timestamp":1506531644000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crirh\/2017\/4029271\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":4,"alternative-id":["4029271","4029271"],"URL":"https:\/\/doi.org\/10.1155\/2017\/4029271","relation":{},"ISSN":["2090-6889","2090-6897"],"issn-type":[{"type":"print","value":"2090-6889"},{"type":"electronic","value":"2090-6897"}],"subject":[],"published":{"date-parts":[[2017]]}}}