{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:13:59Z","timestamp":1762474439748,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T00:00:00Z","timestamp":1491177600000},"content-version":"vor","delay-in-days":92,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Failure to screen susceptible individuals for human leucocyte allele B\u22171502 leads to the onset of Stevens\u2010Johnson syndrome (SJS). We report a case of a 27\u2010year\u2010old Malay female who was treated with carbamazepine following the diagnosis of trigeminal neuralgia without a genetic screening. She was prescribed 150\u2009mg of carbamazepine initially and the dose was increased to 300\u2009mg following the initial dose. A sudden development of skin and mucous membrane ulcers was observed and this warranted immediate hospitalization. A diagnosis of SJS was made and she was treated immediately with intravenous corticosteroids. Genetic screening prior to carbamazepine prescription is essential especially in susceptible populations.<\/jats:p>","DOI":"10.1155\/2017\/4201357","type":"journal-article","created":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T18:03:34Z","timestamp":1491242614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Stevens\u2010Johnson Syndrome following Failure of Genetic Screening prior to Carbamazepine Prescription"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9438-2684","authenticated-orcid":false,"given":"Suraya Ahmad","family":"Nasir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huann Lan","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4827-7984","authenticated-orcid":false,"given":"Hui Jan","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haizal Mohd","family":"Hussaini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7445-0205","authenticated-orcid":false,"given":"Roszalina","family":"Ramli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,3]]},"reference":[{"key":"e_1_2_6_1_2","first-page":"233","article-title":"Pharmacological versus microvascular decompression approaches for the treatment of trigeminal neuralgia: clinical outcomes and direct costs","volume":"4","author":"Lemos L.","year":"2011","journal-title":"Journal of Pain Research"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.57.663.16"},{"key":"e_1_2_6_3_2","first-page":"15","article-title":"Association of HLA-B\u2217 1502 allele and carbamazepine-induced severe adverse cutaneous drug reaction among Asians, a review","volume":"13","author":"Lim K. 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