{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:35:16Z","timestamp":1761863716550,"version":"3.41.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Environmental and Public Health"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Urogenital schistosomiasis is a widely contracted parasitic helminth infection often associated with haematological abnormalities.<jats:italic>Aim<\/jats:italic>. We investigated the relationship between the haematological profile and the intensity of schistosomiasis among children in the Yeji district.<jats:italic>Materials and Methods<\/jats:italic>. A total of 100 participants comprising 50<jats:italic>Schistosoma haematobium<\/jats:italic>(<jats:italic>S. haematobium<\/jats:italic>) infected and 50 noninfected controls aged 6\u201317 years matched for age and sex were recruited into the study. Blood and urine samples were collected and haematological profile and presence of<jats:italic>S. haematobium<\/jats:italic>eggs were assessed using standard protocols.<jats:italic>Results<\/jats:italic>. Haemoglobin (HGB) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>), haematocrit (HCT) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>), mean cell volume (MCV) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.0053<\/mml:mn><\/mml:math>), mean cell haemoglobin (MCH) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.0001<\/mml:mn><\/mml:math>), and mean cell haemoglobin concentration (MCHC) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.005<\/mml:mn><\/mml:math>) levels were reduced in cases compared to controls. Mixed cell percentage (MXD) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.018<\/mml:mn><\/mml:math>) and red blood cell distribution width (RDW-CV) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.012<\/mml:mn><\/mml:math>) were significantly elevated among cases as compared to controls. Haematuria was a clinical characteristic of heavy infection.<jats:italic>Conclusion<\/jats:italic>.<jats:italic>S. haematobium<\/jats:italic>infection creates an imbalance in the haematological profile. We found low HGB, HCT, MCV, MCH, and MCHC levels coupled with increased % MXD count and RDW-CV. Also, low MCV, MCH, and MCHC and high % MXD count are independently associated with<jats:italic>S. haematobium<\/jats:italic>infection among our study participants.<\/jats:p>","DOI":"10.1155\/2017\/4248325","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T21:04:17Z","timestamp":1498079057000},"page":"1-5","source":"Crossref","is-referenced-by-count":9,"title":["Haematological Profile and Intensity of Urogenital Schistosomiasis in Ghanaian Children"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3399-2969","authenticated-orcid":true,"given":"Justice","family":"Afrifa","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desmond","family":"Gyedu","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Ofori Gyamerah","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Cape Coast, Cape Coast, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8618-6648","authenticated-orcid":true,"given":"Samuel","family":"Essien-Baidoo","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac","family":"Mensah-Essilfie","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Science Education, University of Cape Coast, Cape Coast, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1992.47.291"},{"issue":"1","key":"2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1128\/CMR.12.1.97","volume":"12","year":"1999","journal-title":"Clinical Microbiology Reviews"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3185\/pathexo3406"},{"issue":"2","key":"4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.18295\/2075-0528.2627","volume":"6","year":"2006","journal-title":"Sultan qaboos university medical journal"},{"issue":"1","key":"5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.26719\/1999.5.1.177","volume":"5","year":"1999","journal-title":"Eastern Mediterranean Health Journal"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.4314\/njpar.v28i2.37865"},{"issue":"3a","key":"7","first-page":"568","volume":"31","year":"1981","journal-title":"Arzneimittel-Forschung\/Drug Research"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s12639-013-0411-5"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2004.01282.x"},{"issue":"4","key":"10","first-page":"417","volume":"30","year":"1979","journal-title":"Tropenmedizin und Parasitologie"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(64)90185-3"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(05)61013-5"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1990.43.170"},{"issue":"7","key":"15","first-page":"291","volume":"146","year":"2005","journal-title":"Orvosi Hetilap"},{"key":"16","first-page":"135","volume":"15","year":"1994","journal-title":"Egyp J Bilharz"},{"issue":"7","key":"17","first-page":"39","volume":"3","year":"2013","journal-title":"Agriculture and Healthcare"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2005.06.006"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00046-07"},{"issue":"5","key":"20","doi-asserted-by":"crossref","first-page":"939","DOI":"10.4269\/ajtmh.2006.75.939","volume":"75","year":"2006","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"1","key":"21","first-page":"456","volume":"2","year":"2007","journal-title":"The Internet Journal of Laboratory Medicine"},{"issue":"1","key":"22","volume":"4","year":"2009","journal-title":"Internet J. 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