{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:48:07Z","timestamp":1773287287252,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology Research"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Human toxocariasis is caused by several species of the nematode<jats:italic>Toxocara<\/jats:italic>. Two common clinical syndromes are ocular and visceral larva migrans.<jats:italic>Objectives<\/jats:italic>. To determine the<jats:italic>Toxocara<\/jats:italic>antibody positivity in clinically suspected VLM patients and to describe demographic factors and clinical manifestations of seropositive patients.<jats:italic>Methods<\/jats:italic>. 522 clinically suspected patients were studied between 1993 and 2014. Relevant data was gathered from referral letters. Serum samples were subjected to<jats:italic>Toxocara antigen ELISA<\/jats:italic>.<jats:italic>Results<\/jats:italic>. Overall, seropositivity was 50.2% (262), of which 109 (40.8%) were positive at high level of<jats:italic>Toxocara<\/jats:italic>antibody carriage and 153 (58.4%) were positive at low levels. The seropositives ranged from 3 months to 70 years (mean = 7.8). Younger age group had higher levels of seropositivity and it was statistically significant. Majority of children under 5 years were seropositive (47.7%,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">125<\/mml:mn><\/mml:math>). Seropositivity was common in males (55.3%,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">145<\/mml:mn><\/mml:math>). Clinical manifestations of seropositives include lymphadenopathy (24.1%) skin rash (22.5%), dyspnoea (21.7%), fever (21%), hepatosplenomegaly (9.2%), and abdominal pain (3.8%). 197 (75.2%) seropositive cases had eosinophilia. These symptoms were not statistically significant.<jats:italic>Conclusions<\/jats:italic>. This study confirms toxocariasis as an important cause of childhood ill health identifying common clinical symptoms recommending preventive measures to limit transmission.<\/jats:p>","DOI":"10.1155\/2017\/4368659","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T23:30:33Z","timestamp":1512603033000},"page":"1-6","source":"Crossref","is-referenced-by-count":11,"title":["Frequency of Toxocariasis among Patients Clinically Suspected to Have Visceral Toxocariasis: A Retrospective Descriptive Study in Sri Lanka"],"prefix":"10.1155","volume":"2017","author":[{"given":"Devika","family":"Iddawela","sequence":"first","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiruthiha","family":"Ehambaram","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, University of Peradeniya, 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