{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T04:12:25Z","timestamp":1745640745039,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Solitary fibrous tumor is a rare neoplasm of mesenchymal origin that usually affects the pleura. This rarity becomes more relevant in the oral cavity since the clinical features are nonspecific. A 66-year-old female patient presented with a 3-month history of a swelling in the floor of the mouth, measuring 2\u2009cm in greatest diameter, and pain symptomatology. Occlusal and panoramic radiographs showed no bone involvement. Ultrasonography of the submandibular and parotid salivary glands revealed normal morphology, dimensions, and echogenicity. During this exam, a nodular image of low echogenicity measuring about 2.7 \u00d7 1.8\u2009cm was detected. An excisional biopsy was performed and histopathological analysis revealed a well-defined tumor-like lesion with alternation between hypercellular areas without a defined pattern and hypocellular areas. On immunohistochemistry, the tumor was positive for CD34 and CD99 and negative for<jats:italic>\u03b1<\/jats:italic>-SMA, S-100, and bcl-2. Combining the histopathological and immunohistochemical features, the diagnosis was solitary fibrous tumor. The patient is under periodical clinical follow-up and shows no signs of recurrence 7 months after surgical excision of the tumor. The combination of clinical-pathological and immunohistochemical features is necessary for the diagnosis.<\/jats:p>","DOI":"10.1155\/2017\/4395049","type":"journal-article","created":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T17:04:55Z","timestamp":1487869495000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["An Unusual Clinical Presentation of Solitary Fibrous Tumor in the Oral Cavity"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2173-7672","authenticated-orcid":true,"given":"Everton Freitas de","family":"Morais","sequence":"first","affiliation":[{"name":"Oral Pathology Postgraduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah Gondim Lambert","family":"Moreira","sequence":"additional","affiliation":[{"name":"Oral Pathology Postgraduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviane Alves De","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Oral Pathology Postgraduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Rodrigues","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Rocha","family":"Germano","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roseana de Almeida","family":"Freitas","sequence":"additional","affiliation":[{"name":"Oral Pathology Postgraduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"3","key":"1","first-page":"195","volume":"11","year":"2016","journal-title":"Iranian Journal of Pathology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.3948"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2014.1977"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2015.11.001"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51103"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.10.013"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.01.023"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2003.01425.x"},{"issue":"7","key":"9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1177\/014556130608500713","volume":"85","year":"2006","journal-title":"Ear, Nose and Throat Journal"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0119-6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2014.2785"},{"volume":"11, article 28","journal-title":"Archives of Pathology","year":"1931","key":"12"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51256"},{"issue":"2","key":"15","first-page":"73","volume":"48","year":"2010","journal-title":"Patolog\u00eda Revista Latinoamericana"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2014.09.018"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029x.190960"}],"container-title":["Case Reports in Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2017\/4395049.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2017\/4395049.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2017\/4395049.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T21:12:16Z","timestamp":1568841136000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cripa\/2017\/4395049\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":16,"alternative-id":["4395049","4395049"],"URL":"https:\/\/doi.org\/10.1155\/2017\/4395049","relation":{},"ISSN":["2090-6781","2090-679X"],"issn-type":[{"type":"print","value":"2090-6781"},{"type":"electronic","value":"2090-679X"}],"subject":[],"published":{"date-parts":[[2017]]}}}