{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:35:51Z","timestamp":1792690551554,"version":"4.5.0"},"reference-count":67,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,29]],"date-time":"2017-10-29T00:00:00Z","timestamp":1509235200000},"content-version":"vor","delay-in-days":301,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>\n                    The rapid rise of antimicrobial resistance is a worldwide problem. This has necessitated the need to search for new antimicrobial agents. Mushrooms are rich sources of potential antimicrobial agents. This study investigated the antimicrobial properties of methanol extracts of\n                    <jats:italic>Trametes gibbosa<\/jats:italic>\n                    ,\n                    <jats:italic>Trametes elegans<\/jats:italic>\n                    ,\n                    <jats:italic>Schizophyllum commune<\/jats:italic>\n                    , and\n                    <jats:italic>Volvariella volvacea<\/jats:italic>\n                    . Agar well diffusion, broth microdilution, and time\u2010kill kinetic assays were used to determine the antimicrobial activity of the extracts against selected test organisms. Preliminary mycochemical screening revealed the presence of tannins, flavonoids, triterpenoids, anthraquinones, and alkaloids in the extracts. Methanol extracts of\n                    <jats:italic>T. gibbosa, T. elegans, S. commune<\/jats:italic>\n                    , and\n                    <jats:italic>V. volvacea<\/jats:italic>\n                    showed mean zone of growth inhibition of 10.00 \u00b1 0.0 to 21.50 \u00b1 0.84, 10.00 \u00b1 0.0 to 22.00 \u00b1 1.10, 9.00 \u00b1 0.63 to 21.83 \u00b1 1.17, and 12.00 \u00b1 0.0 to 21.17 \u00b1 1.00\u2009mm, respectively. The minimum inhibitory concentration of methanol extracts of\n                    <jats:italic>T. gibbosa, T. elegans, S. commune<\/jats:italic>\n                    , and\n                    <jats:italic>V. volvacea<\/jats:italic>\n                    ranged from 4.0 to 20, 6.0 to 30.0, 8.0 to 10.0, and 6.0 to 20.0\u2009mg\/mL, respectively. Time\u2010kill kinetics studies showed that the extracts possess bacteriostatic action. Methanol extracts of\n                    <jats:italic>T. gibbosa, T. elegans, S. commune<\/jats:italic>\n                    , and\n                    <jats:italic>V. volvacea<\/jats:italic>\n                    exhibited antimicrobial activity and may contain bioactive compounds which may serve as potential antibacterial and antifungal agents.\n                  <\/jats:p>","DOI":"10.1155\/2017\/4534350","type":"journal-article","created":{"date-parts":[[2017,10,29]],"date-time":"2017-10-29T19:30:58Z","timestamp":1509305458000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":128,"title":["Antimicrobial Activities and Time\u2010Kill Kinetics of Extracts of Selected Ghanaian Mushrooms"],"prefix":"10.1155","volume":"2017","author":[{"given":"Theresa","family":"Appiah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaw Duah","family":"Boakye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8515-4882","authenticated-orcid":false,"given":"Christian","family":"Agyare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,29]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1080\/13880200601006897"},{"key":"e_1_2_8_2_2","volume-title":"Antimicrobial Resistance Secretariat","author":"World Health Organization WHO","year":"2017"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1104.041167"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1465-0691.2004.1004.x"},{"key":"e_1_2_8_5_2","unstructured":"World Health Organization (WHO) Human and economic burden. In working to overcome the global impact of neglected tropical diseases First WHO Report on Neglected Tropical Diseases 2017 WHO Geneva Switzerland Doc. WHO\/HTM\/NTD\/2010.1 13-9."},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(05)70051-7"},{"key":"e_1_2_8_7_2","first-page":"26","article-title":"Broadspectrim, a novel antibacterial from Streptomyces sp","volume":"3","author":"Shahghasi A.","year":"2004","journal-title":"Biotechnology"},{"key":"e_1_2_8_8_2","first-page":"159","article-title":"Disruption of Bacterial cell-to-cell communication (Quorum Sensing): a promising novel way to combat bacteria-mediated diseases","volume":"3","author":"Gulgun B. T.","year":"2013","journal-title":"Journal of Marmara University Institute of Health Sciences"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1076\/phbi.39.3.221.5934"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4795-13.2014"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf8003114"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2013.05.003"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2012.10.003"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.9734\/JAMPS\/2015\/20059"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/jam.12196"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.2174\/1389201015666141202152023"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1615\/IntJMedMushrooms.v17.i6.80"},{"key":"e_1_2_8_18_2","first-page":"937","article-title":"Therapeutic potential of Pleurotus ostreatus: A review","volume":"6","author":"Roy A.","year":"2013","journal-title":"Research Journal of Pharmacy and Technology"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2006.01.025"},{"key":"e_1_2_8_20_2","first-page":"45","article-title":"Antimicrobial activity of some macrofungi extracts","volume":"14","author":"Altuner E. M.","year":"2010","journal-title":"Antimicrobial Activity of Some Macrofungi Extracts"},{"key":"e_1_2_8_21_2","first-page":"1","article-title":"Antibacterial Activity of a Mushroom-Stereum ostrea","volume":"2","author":"Praveen K.","year":"2012","journal-title":"Journal of Biology and Agriclture Healthcare"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0964-8305(03)00055-6"},{"key":"e_1_2_8_23_2","first-page":"38","article-title":"Comparative phytochemical evaluation, antimicrobial and antioxidant properties of methanolic and ethanolic extracts of Daedalea elegans\u2014a Nigerian Mushroom","volume":"1","author":"Aina D.","year":"2016","journal-title":"Advance Pharmaceutical Journal"},{"key":"e_1_2_8_24_2","article-title":"Antimicrobial and antioxidant properties of Trametes gibbosa (pers) Fr","volume":"4","author":"Ga J.","year":"2011","journal-title":"Journal of Pharmacy Research"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1039\/c6ra09991b"},{"key":"e_1_2_8_26_2","first-page":"290","article-title":"Cytotoxic activity of methanol extracts from Basidiomycete mushrooms on murine cancer cell lines","volume":"59","author":"Tomasi S.","year":"2004","journal-title":"Die Pharmazie"},{"key":"e_1_2_8_27_2","unstructured":"MbayoM. K. KalondaE. M. TshisandP. T. TatchouaO. KamuleteS. andGlauberK. Chemical Screening of some mushrooms of Katanga (DRC) and their biological activities evaluation 10 2015 435\u2013449."},{"key":"e_1_2_8_28_2","first-page":"103","article-title":"Selenium content and antioxidant potential of some edible wild mushrooms from Bandundu Area, DR Congo","volume":"8","author":"Kabuyi M.","year":"2017","journal-title":"NaturalResources"},{"key":"e_1_2_8_29_2","first-page":"4","article-title":"The use of mushroom glucans and proteoglycans in cancer treatment","volume":"5","author":"Kidd P. M.","year":"2000","journal-title":"Alternative Medicine Review"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-013-1306-4"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.5943\/mycosphere\/7\/2\/4"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-002-1076-7"},{"key":"e_1_2_8_33_2","first-page":"425","article-title":"A research on antimicrobial activity of some macro fungi species","volume":"19","author":"Demirhan A.","year":"2007","journal-title":"Science and Engineering Journal of Firat University"},{"key":"e_1_2_8_34_2","first-page":"6","article-title":"Free radical scavenging activity of fruiting body extracts of an edible mushroom, Volvariella volvacea (Bull.ex Fr.) Singer: an in vitro","volume":"4","author":"Punitha S. C.","year":"2014","journal-title":"Journal of Biomedical and Pharmaceutical Sciences"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201100272"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2008.03.009"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2011.09.005"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2008.04.004"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.4038\/jnsfsr.v29i1-2.2619"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-010-0355-1"},{"key":"e_1_2_8_41_2","first-page":"1554","article-title":"Antimicrobial activities of basidiocarps of wild edible mushrooms of West Bengal, India","volume":"4","author":"Giri S.","year":"2012","journal-title":"International Journal of PharmTech Research"},{"key":"e_1_2_8_42_2","first-page":"55","article-title":"Antimicrobial activities of four wild edible mushrooms in Nigeria","volume":"2","author":"Ayodele S. M. K.","year":"2011","journal-title":"Internatinaol Journl of Science and Nature"},{"key":"e_1_2_8_43_2","volume-title":"Pharmacognosy","author":"Kokate C. K.","year":"2001"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-2933-2.00017-4"},{"key":"e_1_2_8_45_2","first-page":"361","article-title":"Optimization of chromatographic conditions in thin layer chromatography of flavonoids and phenolic acids","volume":"77","author":"Marica M. S.","year":"2010","journal-title":"Croatica Chemica Acta"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/902394"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2006.04.003"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn133"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10295-002-0021-1"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.3923\/ajps.2009.510.514"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf401612t"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2007.06.039"},{"key":"e_1_2_8_53_2","article-title":"Antibacterial activity of the bio-multidrug (Ganoderma lucidum) on Multidrug resistant Staphylococcus aureus (MRSA)","volume":"10","author":"Prasad Y.","year":"2008","journal-title":"Journal of Advanced Biotechnology"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762005000700018"},{"key":"e_1_2_8_55_2","first-page":"629","article-title":"Pharmacokinetics and tissue levels of tilmicosin in fowls","volume":"25","author":"Kele\u015f O.","year":"2001","journal-title":"Turkish Journal of Veterinary & Animal Sciences"},{"key":"e_1_2_8_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)84039-3"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1615\/IntJMedMushrooms.v1.i3.10"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(92)90023-E"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026552024021"},{"key":"e_1_2_8_60_2","first-page":"41","article-title":"Potential antimicrobial activity of red and white wine phenolic extracts against strains of staphylococcus aureus, escherichia coli and Candida albicans","volume":"43","author":"Papadopoulou C.","year":"2005","journal-title":"ood Technology and Biotechnology"},{"key":"e_1_2_8_61_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.1.145-149.2001"},{"key":"e_1_2_8_62_2","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2009.0090"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.02894-14"},{"key":"e_1_2_8_64_2","doi-asserted-by":"publisher","DOI":"10.1086\/381972"},{"key":"e_1_2_8_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2016.02.002"},{"key":"e_1_2_8_66_2","doi-asserted-by":"publisher","DOI":"10.4172\/2161-0444.1000332"},{"key":"e_1_2_8_67_2","first-page":"253","article-title":"Antimicrobial activities and synergistic effects of the combination of some edible mushroom extracts with antibiotics against pathogenic strains","volume":"35","author":"Tinrat S.","year":"2015","journal-title":"International Journal of Pharmaceutical Sciences Review and Research"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2017\/4534350.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2017\/4534350.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2017\/4534350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T21:59:14Z","timestamp":1722895154000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/4534350"}},"subtitle":[],"editor":[{"given":"Letizia","family":"Angiolella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":67,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1155\/2017\/4534350"],"URL":"https:\/\/doi.org\/10.1155\/2017\/4534350","archive":["Portico"],"relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4534350"}}