{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:40:32Z","timestamp":1760132432948,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>To study the effect of intra-abdominal hypertension (IAH) on the frequency of pneumonia with an experimental study, thirteen Sprague-Dawley rats were included. Eight out of thirteen animals were randomly assigned to receive 10\u2009ml of benzalkonium chloride 0.2% (megacolon group) and five animals received 10\u2009ml NaCl 0.9% (controls). Animals were anaesthetized by intramuscular delivery of ketamine. The incidence of positivity for bacteria lung tissue cultures and mesenteric lymph node cultures was assessed at the 21st day after animals\u2019 sacrification, or before in case of death. All megacolon group animals presented progressive increase of the abdomen and increased IAP (\u226510\u2009mmHg) whereas the frequency of their evacuations was almost eliminated. Controls presented normal evacuations, no sign of abdominal distention, and normal IAP. In megacolon group animals, there was evidence of significant amount of bacteria in lung cultures. In contrast, no bacteria were found in control animals.<\/jats:p>","DOI":"10.1155\/2017\/4601348","type":"journal-article","created":{"date-parts":[[2017,3,5]],"date-time":"2017-03-05T16:02:03Z","timestamp":1488729723000},"page":"1-7","source":"Crossref","is-referenced-by-count":6,"title":["Intra-Abdominal Hypertension Causes Bacterial Growth in Lungs: An Animal Study"],"prefix":"10.1155","volume":"2017","author":[{"given":"Eleni","family":"Papakrivou","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larissa, University of Thessaly School of Medicine, Larisa, Greece"},{"name":"Department of Pediatric Surgery, General Hospital of \u201cG. Gennimatas\u201d, A\u2019 University Department, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1951-6421","authenticated-orcid":true,"given":"Demosthenes","family":"Makris","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larissa, University of Thessaly School of Medicine, Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efstratios","family":"Manoulakas","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larissa, University of Thessaly School of Medicine, Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda","family":"Mitroudi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, General Hospital of \u201cG. Gennimatas\u201d, A\u2019 University Department, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Tepetes","sequence":"additional","affiliation":[{"name":"Department of General Surgery, University Hospital of Larisa, University of Thessaly School of Medicine, Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Papazoglou","sequence":"additional","affiliation":[{"name":"Department of Pathologo-Anatomy, General Hospital of \u201cG. Gennimatas\u201d, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Epaminondas","family":"Zakynthinos","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larissa, University of Thessaly School of Medicine, Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2008.09.003"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2906-z"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200209-1060oc"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199811000-00013"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2011.03.001"},{"issue":"154\u2013162","key":"6","volume":"47","year":"2015","journal-title":"Anaesthiology Intensive Therapy"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2906-z"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.4103\/2153-3539.92034"},{"issue":"2","key":"9","first-page":"115","volume":"18","year":"2009","journal-title":"Advances in Clinical and Experimental Medicine"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1970.01340280036010"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2008.06.006"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.12.1351"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199711000-00019"},{"key":"17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/978-1-4615-4143-1_2","volume":"473","year":"1999","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.7.1054"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000157303.76749.9b"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200112000-00008"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.90825.2008"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201104-0630OC"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(93)90232-A"},{"key":"22","first-page":"399","volume":"13","year":"2005","journal-title":"Journal of Pediatric Surgery"},{"issue":"3","key":"23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000200239","volume":"45","year":"1990","journal-title":"Digestion"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0922-6"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2013.17.2.44"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-007-0088-0"},{"key":"27","first-page":"437","volume":"4","year":"2011","journal-title":"Forensic Pathology Reviews"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/4601348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/4601348.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2017\/4601348.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T05:23:38Z","timestamp":1568870618000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2017\/4601348\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":26,"alternative-id":["4601348","4601348"],"URL":"https:\/\/doi.org\/10.1155\/2017\/4601348","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"type":"print","value":"2314-6133"},{"type":"electronic","value":"2314-6141"}],"subject":[],"published":{"date-parts":[[2017]]}}}