{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:36:19Z","timestamp":1789583779211,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Sporotrichosis is a human and animal disease caused by species of the<jats:italic>Sporothrix schenckii<\/jats:italic>complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms. These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement. He had an extremely low CD4 cell count (06\/<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:msup><mml:mrow><mml:mi mathvariant=\"normal\">m<\/mml:mi><mml:mi mathvariant=\"normal\">m<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn fontstyle=\"italic\">3<\/mml:mn><\/mml:mrow><\/mml:msup><\/mml:mrow><\/mml:math>). Treatment with amphotericin B deoxycholate led to complete clinical resolution. Sporotrichosis remains a neglected opportunistic infection among HIV-infected patients in Rio de Janeiro state, Brazil, and awareness of this potentially fatal infection is of utmost importance if treatment is not to be delayed and if potentially devastating complications are to be avoided.<\/jats:p>","DOI":"10.1155\/2017\/4713140","type":"journal-article","created":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T21:01:21Z","timestamp":1506373281000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count"],"prefix":"10.1155","volume":"2017","author":[{"given":"Isis Cristine Mor\u00e1via Ribeiro","family":"de Oliveira-Esteves","sequence":"first","affiliation":[{"name":"Hospital Universit\u00e1rio Gaffr\u00e9e e Guinle, Centro de Ci\u00eancias Biol\u00f3gicas e da Sa\u00fade, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), 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