{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T03:50:45Z","timestamp":1784692245437,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Cholesterol granuloma of the middle ear is extremely rare in comparison to cholesterol granuloma of the petrous apex but sometimes shows an aggressive course.<jats:italic>Case Report<\/jats:italic>. We report herein a case involving a large, aggressive cholesterol granuloma of the middle ear that eroded the middle cranial fossa. A 64-year-old woman presented with pain in the left ear and hearing loss. Cholesterol granuloma was finally diagnosed from diffusion-weighted imaging, and cortical mastoidectomy was performed with canal wall down tympanoplasty type III. Recovery was uneventful recovery and the patient well at the 3-year follow-up.<jats:italic>Conclusion<\/jats:italic>. This case demonstrates the rare but clinically important pathology of aggressive cholesterol granuloma of the middle ear.<\/jats:p>","DOI":"10.1155\/2017\/4793786","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T17:08:06Z","timestamp":1498151286000},"page":"1-5","source":"Crossref","is-referenced-by-count":15,"title":["Large Cholesterol Granuloma of the Middle Ear Eroding into the Middle Cranial Fossa"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8797-223X","authenticated-orcid":true,"given":"Tessei","family":"Kuruma","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tohru","family":"Tanigawa","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasue","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ogawa","family":"Tetsuya","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Aichi Medical University, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1258\/002221505775010661","volume":"119","year":"2005","journal-title":"J Otology & Laryngology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31802bea4b"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200207000-00023"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050160"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000303"},{"key":"6","first-page":"825","volume":"8","year":"1987","journal-title":"AJNR AM J Neuroradical"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310017036"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.181.1.1810261"},{"key":"9","year":"1993"},{"issue":"3","key":"10","first-page":"82","volume":"2","year":"2009","journal-title":"Otorhinolaryngologist"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200301000-00020"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318271c4aa"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31821c64b2"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(89)90034-3"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.91391"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31825d63ea"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2017\/4793786.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2017\/4793786.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2017\/4793786.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T12:05:10Z","timestamp":1569499510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criot\/2017\/4793786\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":16,"alternative-id":["4793786","4793786"],"URL":"https:\/\/doi.org\/10.1155\/2017\/4793786","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"value":"2090-6765","type":"print"},{"value":"2090-6773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}