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In line with this modern paradigm and as a follow-up to our previous studies, the present study is designed to investigate the crude methanolic extracts and subsequent CHCl<jats:sub>3<\/jats:sub>,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>n<\/mml:mi><\/mml:mrow><\/mml:math>-BuOH, and H<jats:sub>2<\/jats:sub>O fractions of<jats:italic>Acalypha alnifolia<\/jats:italic>,<jats:italic>Pavetta indica,<\/jats:italic>and<jats:italic>Ochna obtusata<\/jats:italic>for their inhibitory activities towards specific targets involved in AD and DM, namely, acetylcholinesterase, butyrylcholinesterase, and<jats:italic>\u03b1<\/jats:italic>-glucosidase (<jats:italic>\u03b1<\/jats:italic>-Glc). The methanolic extract and its derived chloroform fractions exhibited remarkable inhibitory capacities with IC<jats:sub>50<\/jats:sub>values being found at the<jats:italic>\u03bc<\/jats:italic>g\/mL level. Further studies on most active chloroform fractions presented a prominent ability to scavenge DPPH and ABTS reactive species and highest neuroprotective effect against H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>induced cell injury. Phytochemical analysis showed a large amount of phenolics, flavonoids, and terpenoids in active fractions. In conclusion,<jats:italic>A. alnifolia<\/jats:italic>,<jats:italic>P. indica,<\/jats:italic>and<jats:italic>O. obtusata<\/jats:italic>could be promising sources for the treatment of AD and DM since these fractions induced significant anticholinesterase, antidiabetic, antioxidant, and neuroprotection effects attributable to phenolic, flavonoid, and terpenoid contents and encourage further studies for development of multifunctional therapeutic agent for AD and DM dual therapy.<\/jats:p>","DOI":"10.1155\/2017\/5140506","type":"journal-article","created":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T23:31:28Z","timestamp":1508887888000},"page":"1-12","source":"Crossref","is-referenced-by-count":15,"title":["<i>In Vitro<\/i>Screening of Three Indian Medicinal Plants for Their Phytochemicals, Anticholinesterase, Antiglucosidase, Antioxidant, and Neuroprotective 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