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Their exact ecological niche remains unknown; however, they have been isolated from soil samples and armadillos (<jats:italic>Dasypus novemcinctus<\/jats:italic>), which have been proposed as animal reservoir for these fungi. Human infection occurs by inhalation of conidia or mycelia fragments and is mostly associated with immunocompetent hosts inhabiting and\/or working in endemic rural areas. In this review focusing on the pathogen perspective, we will discuss some of the microbial attributes and molecular mechanisms that enable<jats:italic>Paracoccidioides<\/jats:italic>spp. to tolerate, adapt, and ultimately avoid the host immune response, establishing infection.<\/jats:p>","DOI":"10.1155\/2017\/5313691","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T21:00:44Z","timestamp":1493758844000},"page":"1-19","source":"Crossref","is-referenced-by-count":45,"title":["<i>Paracoccidioides<\/i>Spp.: Virulence Factors and Immune-Evasion Strategies"],"prefix":"10.1155","volume":"2017","author":[{"given":"Emma","family":"Camacho","sequence":"first","affiliation":[{"name":"Department of Molecular Microbiology and Immunobiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 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