{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:35:53Z","timestamp":1740148553450,"version":"3.37.3"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sensors"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Antibiotics are nowadays used and abused worldwide in common veterinary practice to treat diseases, prevent infections, and promote animal\u2019s growth. Drug resistance occurrence is a relevant phenomenon that can inactivate the antibiotic. Moreover, antibiotics used for animals are also found in milk and it poses serious health risks to humans. Another negative effect is related to milk processors since antibiotics cause detrimental effects on cheese and yogurt starter bacteria. Given its consumption as both beverage and derivatives, milk is one of the most regulated products in food industry. Nowadays several commercial tests are available to investigate antibiotics in milk, but they generally provide a qualitative result, require bulky procedure, and are time consuming. In this paper, we investigate the use of a chromogenic cephalosporin to quantify the concentration of cloxacillin\u2014a<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>\u03b2<\/mml:mi><mml:mtext>-<\/mml:mtext><\/mml:math>lactam difficult to be detected by using \u201ccowside\u201d screenings which is the drug of choice in the method of mastitis control. The proposed measurement method and prototype have been demonstrated to be able to detect cloxacillin in milk at concentrations lower than the MRL set by the European Commission. Moreover, they are also able to detect the illegal practice of using<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>\u03b2<\/mml:mi><mml:mtext>-<\/mml:mtext><\/mml:math>lactamase to degrade<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>\u03b2<\/mml:mi><mml:mtext>-<\/mml:mtext><\/mml:math>lactams in milk.<\/jats:p>","DOI":"10.1155\/2017\/5742359","type":"journal-article","created":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T21:02:36Z","timestamp":1504126956000},"page":"1-11","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility Study on a Measurement Method and a Portable Measuring System to Estimate the Concentration of Cloxacillin and<i>\u03b2<\/i>-Lactamase in Milk"],"prefix":"10.1155","volume":"2017","author":[{"given":"Luca","family":"Ferrari","sequence":"first","affiliation":[{"name":"CNH Industrial, Viale delle Nazioni 55, 41122 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Rovati","sequence":"additional","affiliation":[{"name":"Department of Engineering \u201cE. Ferrari\u201d, University of Modena and Reggio Emilia, Via Vivarelli 10, 41125 Modena, Italy"},{"name":"Science & Technology Park for Medicine, TPM, Via 29 Maggio 6, 41037 Mirandola, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Paola","family":"Costi","sequence":"additional","affiliation":[{"name":"Tydock Pharma Srl, Strada Gherbella 294\/b, 41126 Modena, Italy"},{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 287, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosaria","family":"Luciani","sequence":"additional","affiliation":[{"name":"Tydock Pharma Srl, Strada Gherbella 294\/b, 41126 Modena, Italy"},{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 287, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3797-7427","authenticated-orcid":true,"given":"Alberto","family":"Venturelli","sequence":"additional","affiliation":[{"name":"Tydock Pharma Srl, Strada Gherbella 294\/b, 41126 Modena, Italy"},{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 287, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7466-9629","authenticated-orcid":true,"given":"Stefano","family":"Cattini","sequence":"additional","affiliation":[{"name":"Department of Engineering \u201cE. 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