{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T11:15:27Z","timestamp":1767093327496,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Granuloma annulare (GA) is a benign inflammatory dermatosis characterized clinically by dermal papules and annular plaques. The pathogenesis of GA is not well understood, although it is thought to result from a delayed-type hypersensitivity reaction in which inflammatory cells elicit connective tissue degradation. This condition has been seen following the use of several drugs, including tumor necrosis factor-alpha (TNF-<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>\u03b1<\/mml:mi><\/mml:mrow><\/mml:math>) inhibitors, which paradoxically have also been reported to treat GA. We report the case of a patient who developed GA in association with secukinumab, an interleukin-17A antagonist, and discuss its implications for our understanding of the pathogenesis of GA.<\/jats:p>","DOI":"10.1155\/2017\/5918708","type":"journal-article","created":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T17:08:41Z","timestamp":1495472921000},"page":"1-4","source":"Crossref","is-referenced-by-count":9,"title":["A Case of Granuloma Annulare Associated with Secukinumab Use"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0353-9437","authenticated-orcid":true,"given":"Lauren","family":"Bonomo","sequence":"first","affiliation":[{"name":"Department of Dermatology, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, 5th Floor, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4548-6318","authenticated-orcid":true,"given":"Sara","family":"Ghoneim","sequence":"additional","affiliation":[{"name":"Saba University School of Medicine, The Bottom, Saba, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7250-285X","authenticated-orcid":true,"given":"Jacob","family":"Levitt","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, 5th Floor, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0029-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.075663"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)70231-3"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1159\/000248911"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2010.0071"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200304070-00001"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s004030000150"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2007.10.001"},{"issue":"1","key":"9","first-page":"107","volume":"29","year":"2002","journal-title":"Journal of Rheumatology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09923.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1412679"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1314258"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06371.x"}],"container-title":["Case Reports in Dermatological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2017\/5918708.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2017\/5918708.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2017\/5918708.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T17:08:41Z","timestamp":1495472921000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cridm\/2017\/5918708\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":13,"alternative-id":["5918708","5918708"],"URL":"https:\/\/doi.org\/10.1155\/2017\/5918708","relation":{},"ISSN":["2090-6463","2090-6471"],"issn-type":[{"type":"print","value":"2090-6463"},{"type":"electronic","value":"2090-6471"}],"subject":[],"published":{"date-parts":[[2017]]}}}