{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:06:19Z","timestamp":1778569579916,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T00:00:00Z","timestamp":1491782400000},"content-version":"vor","delay-in-days":99,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Cytomegalovirus (CMV) is the most common cause of intrauterine infection, occurring in up to 2% of all live births. Most women are asymptomatic or experience nonspecific symptoms, which can lead to long\u2010term sequelae in newborns including neurological impairment, hearing loss, and mental retardation. A 41\u2010year\u2010old woman (G6 P2), with a medical history of epilepsy, presented for her routine anomaly scan at 20 + 4\/40. A single finding of echogenic bowel was noted on ultrasound which prompted a full investigation. A repeat ultrasound only five days later demonstrated progressive changes, which included bilateral ventriculomegaly with oedema of the posterior ventricular wall, periventricular hyperechogenicity, and enlargement of the cisterna magna. CMV DNA was detected at amniocentesis. Ultrasound findings are not diagnostic for CMV with only 11\u201315% of at\u2010risk fetuses being identified. Unfortunately, these findings may be the only indication of an abnormality. There is a well\u2010documented lack of awareness surrounding CMV and screening is not routinely offered. Given the risk to the pregnancy of CMV and to subsequent pregnancies, simple education at the start of a pregnancy could significantly reduce the incidence of maternal CMV.<\/jats:p>","DOI":"10.1155\/2017\/5928398","type":"journal-article","created":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T17:02:00Z","timestamp":1491843720000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sequence and Timing of Intracranial Changes in Cytomegalovirus in Pregnancy: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2017","author":[{"given":"Cynthia","family":"O\u2019Sullivan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0716-4641","authenticated-orcid":false,"given":"Shankari","family":"Arulkumaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorin","family":"Lakasing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Jauniaux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,10]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.09.052"},{"key":"e_1_2_6_2_2","first-page":"28","article-title":"Fetal cytomegalovirus infection of the brain: the spectrum of sonographic findings","volume":"24","author":"Malinger G.","year":"2003","journal-title":"American Journal of Neuroradiology"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4340"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000330636"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-86702008000100009"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2007.10.015"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2005.09.015"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.15.1.7899609"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.73.5.611"},{"key":"e_1_2_6_10_2","first-page":"703","article-title":"Congenital cytomegalovirus infection of the brain: imaging analysis and embryologic considerations","volume":"15","author":"Barkovich A. 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