{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T18:15:24Z","timestamp":1770488124875,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic>To analyze the outcomes and difference after UVA\/riboflavin corneal collagen crosslinking (CXL) in four different corneal thickness groups of patients with progressive keratoconus.<jats:italic>Methods.<\/jats:italic>Retrospective study. Eyes with progressive keratoconus after CXL were divided into 4 subgroups as follows: group 1, thinnest corneal thickness (TCT) \u2264\u2009400\u2009<jats:italic>\u00b5<\/jats:italic>m; group 2, 400\u2009<jats:italic>\u00b5<\/jats:italic>m &lt;\u2009TCT \u2264\u2009450\u2009<jats:italic>\u00b5<\/jats:italic>m; group 3, 450\u2009<jats:italic>\u00b5<\/jats:italic>m &lt;\u2009TCT\u2009\u2264\u2009500\u2009<jats:italic>\u00b5<\/jats:italic>m; group 4, TCT \u2265\u2009500\u2009<jats:italic>\u00b5<\/jats:italic>m. Baseline, 6-month, and 12-month visual acuity, corneal topography, TCT, and endothelial cell density were evaluated.<jats:italic>Results.<\/jats:italic>The analysis included 123 eyes of 101 patients. At 6 and 12 months after CXL, there was a mean improvement about visual acuity and keratometry values in all patients. There was a reduction in the change of maximum keratometry (<jats:italic>K<\/jats:italic><jats:sub>max<\/jats:sub>) with the increase of TCT. After 1 year of treatment, it was 3.04\u2009\u00b1\u20090.75\u2009D in group 1, 2.38\u2009\u00b1\u20090.51\u2009D in group 2, 1.57\u2009\u00b1\u20090.35\u2009D in group 3, and 0.31\u2009\u00b1\u20090.20\u2009D in group 4.<jats:italic>Conclusion.<\/jats:italic>CXL is successful in halting the progression of keratoconus and there was a negative linear correlation between TCT and<jats:italic>K<\/jats:italic><jats:sub>max<\/jats:sub>. Advanced cases of progressive keratoconus seemed to obtain more benefits from the flatting effects of CXL.<\/jats:p>","DOI":"10.1155\/2017\/6490915","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T17:09:32Z","timestamp":1489511372000},"page":"1-7","source":"Crossref","is-referenced-by-count":22,"title":["Thinner Corneas Appear to Have More Striking Effects of Corneal Collagen Crosslinking in Patients with Progressive Keratoconus"],"prefix":"10.1155","volume":"2017","author":[{"given":"Yunfei","family":"Han","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China"},{"name":"Department of Ophthalmology, The Second People\u2019s Hospital of Liaocheng, Linqing 252600, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanyun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shandong 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