{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:57:27Z","timestamp":1788386247270,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2017]]},"abstract":"\n Background<\/jats:italic>\n . Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life.\n Methods.<\/jats:italic>\n Prevalence of anxiety and depression was assessed in IBD outpatients through retrospective chart review. The presence of anxiety and\/or depression was determined using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 self-report questionnaires or by diagnosis through psychiatric interview. Patient demographics, disease characteristics, and medication information were also collected. Multivariable analysis was used to determine associations between patient factors and depression and anxiety.\n Results.<\/jats:italic>\n 327 patient charts were reviewed. Rates of depression and anxiety were found to be 25.8% and 21.2%, with 30.3% of patients suffering from depression and\/or anxiety. Disease activity was found to be significantly associated with depression and\/or anxiety (\n \n p<\/mml:mi>\n =<\/mml:mo>\n 0.01<\/mml:mn>\n <\/mml:math>\n ). Females were more likely to have anxiety (\n \n p<\/mml:mi>\n =<\/mml:mo>\n 0.01<\/mml:mn>\n <\/mml:math>\n ).\n Conclusion.<\/jats:italic>\n A significant proportion of IBD patients suffer from depression and\/or anxiety. The rates of these mental illnesses would justify screening and referral for psychiatric treatment in clinics treating this population. Patients with active disease are particularly at risk for anxiety and depression.\n <\/jats:p>","DOI":"10.1155\/2017\/6496727","type":"journal-article","created":{"date-parts":[[2017,10,18]],"date-time":"2017-10-18T19:32:09Z","timestamp":1508355129000},"page":"1-6","source":"Crossref","is-referenced-by-count":192,"title":["Prevalence of Anxiety and Depression in Patients with Inflammatory Bowel Disease"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4193-1314","authenticated-orcid":true,"given":"Glynis","family":"Byrne","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Rosenfeld","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8699-4370","authenticated-orcid":true,"given":"Yvette","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Qian","sequence":"additional","affiliation":[{"name":"Centre for Health Evaluation and Outcome Sciences, University of British Columbia, St. Paul\u2019s Hospital, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Raudzus","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Nunez","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-8209","authenticated-orcid":true,"given":"Brian","family":"Bressler","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"7","key":"1","first-page":"S54","volume":"190","year":"2009","journal-title":"Med. 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