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(a) To determine associations among motor evoked potential (MEP) amplitude, MEP latency, lower extremity (LE) impairment, and gait velocity and (b) determine the association between the presence of a detectable MEP signal with LE impairment and with gait velocity.<jats:italic>Method<\/jats:italic>. 35 subjects with chronic, stable LE hemiparesis were undergone TMS, the LE section of the Fugl-Meyer Impairment Scale (LE FM), and 10-meter walk test. We recorded presence, amplitude, and latency of MEPs in the affected tibialis anterior (TA) and soleus (SO).<jats:italic>Results<\/jats:italic>. MEP presence was associated with higher LEFM scores in both the TA and SO. MEP latency was larger in subjects with lower LEFM and difficulty walking.<jats:italic>Conclusion<\/jats:italic>. MEP latency appears to be an indicator of LE impairment and gait.<jats:italic>Significance<\/jats:italic>. Our results support the precept of using TMS, particularly MEP latency, as an adjunctive LE outcome measurement and prognostic technique.<\/jats:p>","DOI":"10.1155\/2017\/6971206","type":"journal-article","created":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T21:06:47Z","timestamp":1485292007000},"page":"1-7","source":"Crossref","is-referenced-by-count":16,"title":["Navigated Transcranial Magnetic Stimulation: A Biologically Based Assay of Lower Extremity Impairment and Gait Velocity"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9059-1056","authenticated-orcid":true,"given":"Heather T.","family":"Peters","sequence":"first","affiliation":[{"name":"Division of Occupational Therapy, The Ohio State University, Columbus, OH, USA"},{"name":"B.R.A.I.N. 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