{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T06:08:23Z","timestamp":1782540503239,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,12]],"date-time":"2017-11-12T00:00:00Z","timestamp":1510444800000},"content-version":"vor","delay-in-days":315,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11374016"],"award-info":[{"award-number":["11374016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003213","name":"Beijing Municipal Education Commission","doi-asserted-by":"publisher","award":["YETP0789"],"award-info":[{"award-number":["YETP0789"]}],"id":[{"id":"10.13039\/501100003213","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>The 4 properties of Chinese <jats:italic>materia medica<\/jats:italic> refer to cold, hot, warm, and cool. In the present study, the effects of the <jats:italic>Coptis<\/jats:italic>, the prepared aconite root, and dried ginger rhizome were compared with regard to the rectal and skin temperature changes of the related body surface acupuncture points (Dazhui, Zhiyang, Mingmen, Zhongwan, and Shenque). The investigation aimed to explore the thermal sensitive points, which can reflect the cold and hot properties of the Chinese herbs. This study showed that the prepared aconite root and dried ginger rhizome exhibited a warming effect on the body temperature, whereas the warming sensitive points were Zhongwan, Shenque, Dazhui, and Zhiyang. <jats:italic>Coptis<\/jats:italic> exhibited both a warming and a cooling effect on the body temperature, and the cooling sensitive point was Dazhui. The concomitant effect of these three Chinese herbs on the regulation of the body temperature was reflected by Dazhui. However, there are still some limitations and one\u2010sidedness. For instance, the cold and hot property of some herbs cannot be fully reflected through relevant acupoints on the conception and governor vessels. More detecting sites such as ears and internal organs will be selected for further exploration of Chinese herbs\u2019 cold and hot property.<\/jats:p>","DOI":"10.1155\/2017\/7250340","type":"journal-article","created":{"date-parts":[[2017,11,12]],"date-time":"2017-11-12T23:33:37Z","timestamp":1510529617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Effects of Natural Chinese Medicine Aconite Root, Dried Ginger Rhizome, and <i>Coptis<\/i> on Rectal and Skin Temperatures at Acupuncture Points"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7670-1979","authenticated-orcid":false,"given":"Jia-Min","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Xi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9244-2436","authenticated-orcid":false,"given":"Feng-Jie","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6999-2640","authenticated-orcid":false,"given":"Yan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7383-3327","authenticated-orcid":false,"given":"Yu-Shan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2502-6453","authenticated-orcid":false,"given":"Peng-Fei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6015-9177","authenticated-orcid":false,"given":"Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Yao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9567-5980","authenticated-orcid":false,"given":"Sheng-Yong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1893-2530","authenticated-orcid":false,"given":"Yu-Hang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,12]]},"reference":[{"key":"e_1_2_8_1_2","volume-title":"Chinese Herbal Medicines","author":"Liu G. W.","year":"2001"},{"key":"e_1_2_8_2_2","first-page":"55","article-title":"Discussion of the four properties and five flavors of Chinese herbal medicine","volume":"1","author":"Liang S. M.","year":"1982","journal-title":"New Journal of Traditional Chinese Medicine"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/595963"},{"key":"e_1_2_8_4_2","volume-title":"Fundamentals of Formulas of Chinese Medicine","author":"Liu G. W.","year":"2002"},{"key":"e_1_2_8_5_2","first-page":"548","article-title":"The cold and hot quantification of Chinese herbs and the principle of the minimum amount of cold and hot quantification","volume":"44","author":"Jiang X. B.","year":"2003","journal-title":"Journal of Traditional Chinese Medicine"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.3736\/jcim20121007"},{"key":"e_1_2_8_7_2","first-page":"1529","article-title":"Hypotheses of macroscopic drug nature and numerical simulation of component drug nature of traditional","volume":"14","author":"Wang H. W.","year":"2012","journal-title":"World Science and Technology\/Modernization of Traditional Chinese Medicine and Materia Medica"},{"key":"e_1_2_8_8_2","first-page":"17","article-title":"The research of formula quantification based on the four-property theory of Chinese medicine","volume":"10","author":"Sun Y.","year":"2015","journal-title":"World Chinese Medicine"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-009-0146-9"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0254-6272(13)60013-8"},{"key":"e_1_2_8_11_2","first-page":"53","article-title":"Application of TTM system for testing Chinese herbal nature","volume":"12","author":"Zhu M.","year":"2007","journal-title":"Chinese Journal of Stereology and Mage Rectalysis"},{"key":"e_1_2_8_12_2","first-page":"10","article-title":"A Microcalorimetric Research on the effect of traditional Chinese medicine on the growth and metabolism of E. coli","volume":"37","author":"Gao Y. S.","year":"2014","journal-title":"Journal of Yunnan University of Traditional Chinese Medicine"},{"key":"e_1_2_8_13_2","first-page":"1122","article-title":"Experimental method for evaluating cold and hot characteristic of traditional Chinese medicine","volume":"41","author":"Cheng W.-W.","year":"2010","journal-title":"Chinese Traditional and Herbal Drugs"},{"key":"e_1_2_8_14_2","first-page":"359","article-title":"Evaluation of cold-heat characteristics of Pulsatillae Radix","volume":"36","author":"Wang Z.","year":"2013","journal-title":"Drug Evaluation Research"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-014-0349-y"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.5582\/bst.2011.v5.3.89"},{"key":"e_1_2_8_17_2","volume-title":"Effects of Mankshood, Dry ginger, Chinese goldthread, Rhubarb on signs of cold and heat and on energy metabolism in rats","author":"Ma Q. C.","year":"2007"},{"key":"e_1_2_8_18_2","first-page":"39","article-title":"Research on four nature drugs about fat metabolism in rats","volume":"6","author":"Zhou R.","year":"2010","journal-title":"Asia-Pacific Traditional Medicine"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.B1400189"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054234"},{"key":"e_1_2_8_21_2","first-page":"785","article-title":"Study on infrared thermal imaging of rat model with cold and hot syndromes","volume":"35","author":"Yuan Y. M.","year":"2008","journal-title":"Liaoning Journal of Traditional Chinese Medicine"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/748041"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0117907"},{"key":"e_1_2_8_24_2","first-page":"1069","article-title":"Dose conversion among different animals and healthy volunteers in pharmacological study","volume":"9","author":"Huang H. J.","year":"2004","journal-title":"Chinese Journal of Clinical Pharmacology and Therapeutics"},{"key":"e_1_2_8_25_2","volume-title":"Experimental acupuncture science","author":"Zhang L. F.","year":"2010"},{"key":"e_1_2_8_26_2","volume-title":"Chinese Herbal Medicinal","author":"Gao X. M.","year":"2013"},{"key":"e_1_2_8_27_2","first-page":"456","article-title":"Clinical research progress of Zhongwan in recent years","volume":"31","author":"Zuo T. W.","year":"2011","journal-title":"Harbin Medical Journal"},{"key":"e_1_2_8_28_2","first-page":"29","article-title":"Exploration of the meridian and collateral distribution of Zhongwan","volume":"1","author":"Wei C. J.","year":"1989","journal-title":"Traditional Chinese Clinical and Healthcare Medicine"},{"key":"e_1_2_8_29_2","first-page":"12","article-title":"Textual research on acupuncture and moxibustion of Shenque","author":"Wu X. G.","year":"2011","journal-title":"Chinese Society of Acupuncture andMoxibustion"},{"key":"e_1_2_8_30_2","first-page":"623","article-title":"Clinical treatment of Zhi Yang points","volume":"36","author":"Zhao L. L.","year":"2016","journal-title":"Jilin Journal of Traditional Chinese Medicine"},{"key":"e_1_2_8_31_2","first-page":"32","article-title":"A study and explanation on acupoint Dazhui (GV14)","volume":"30","author":"Cao W. Z.","year":"2012","journal-title":"Journal of Sichuan of Traditional Chinese Medicine"},{"key":"e_1_2_8_32_2","first-page":"446","article-title":"Assessing drug targeting of Yougui Pill, Zuogui Pill, and their disassembled prescriptions using infrared thermography","volume":"34","author":"Zheng X.","year":"2014","journal-title":"Zhongguo Zhongxiyi Jiehe Zazhi"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0104320"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2017\/7250340.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2017\/7250340.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2017\/7250340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T02:04:04Z","timestamp":1722909844000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/7250340"}},"subtitle":[],"editor":[{"given":"Raffaele","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1155\/2017\/7250340"],"URL":"https:\/\/doi.org\/10.1155\/2017\/7250340","archive":["Portico"],"relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7250340"}}