{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:26:52Z","timestamp":1790162812819,"version":"4.1.0"},"reference-count":110,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T00:00:00Z","timestamp":1508803200000},"content-version":"vor","delay-in-days":296,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["2014 SGR 773"],"award-info":[{"award-number":["2014 SGR 773"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006135","name":"ERAB: The European Foundation for Alcohol Research","doi-asserted-by":"publisher","award":["EA1517"],"award-info":[{"award-number":["EA1517"]}],"id":[{"id":"10.13039\/501100006135","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006135","name":"ERAB: The European Foundation for Alcohol Research","doi-asserted-by":"publisher","award":["EA 1515"],"award-info":[{"award-number":["EA 1515"]}],"id":[{"id":"10.13039\/501100006135","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006135","name":"ERAB: The European Foundation for Alcohol Research","doi-asserted-by":"publisher","award":["EA 1514"],"award-info":[{"award-number":["EA 1514"]}],"id":[{"id":"10.13039\/501100006135","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006135","name":"ERAB: The European Foundation for Alcohol Research","doi-asserted-by":"publisher","award":["EA 1324"],"award-info":[{"award-number":["EA 1324"]}],"id":[{"id":"10.13039\/501100006135","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Polyphenols have an important protective role against a number of diseases, such as atherosclerosis, brain dysfunction, stroke, cardiovascular diseases, and cancer. Cardiovascular diseases are the number one cause of death worldwide: more people die annually from cardiovascular diseases than from any other cause. The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use, and excess alcohol intake. The dietary consumption of polyphenols has shown to be inversely associated with morbidity and mortality by cardio\u2010 and cerebrovascular diseases. It is well\u2010known that the protective effects of polyphenols <jats:italic>in vivo<\/jats:italic> depend on the grade how they are extracted from food and on their intestinal absorption, metabolism, and biological action with target tissues. The aim of this review was to summarise the relation between polyphenols of different plant sources and stroke in human intervention studies, animal models, and in vitro studies.<\/jats:p>","DOI":"10.1155\/2017\/7467962","type":"journal-article","created":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T23:34:12Z","timestamp":1508888052000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Dietary Polyphenols in the Prevention of Stroke"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7022-9041","authenticated-orcid":false,"given":"A.","family":"Tressera-Rimbau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0411-9784","authenticated-orcid":false,"given":"S.","family":"Arranz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Eder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6287-799X","authenticated-orcid":false,"given":"A.","family":"Vallverd\u00fa-Queralt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,24]]},"reference":[{"key":"e_1_2_8_1_2","volume-title":"Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects against Chronic Diseases","author":"Del Rio D.","year":"2013"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397934-6.00014-0"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/b802662a"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2015.02.098"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.10.3275S"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2007.01.006"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17030337"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408390802066805"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2009.08.008"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2013.12.106"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2013.11.158"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-309647"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201500820"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408391003698677"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2012.09.009"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.2174\/1389557511313080002"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf504185s"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2014.03.016"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.3945\/an.116.014050"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.303374"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.211557"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2014.07.008"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2010.227"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2012.25"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-12-147"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpt176"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0620-z"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-309218"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2014.09.001"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2572606"},{"key":"e_1_2_8_31_2","first-page":"1","volume-title":"Unit: Public Health Aspects of Stroke Workbook","author":"Abbott H.","year":"2010"},{"key":"e_1_2_8_32_2","volume-title":"Priority Medicines for Europe and the World \u201cA Public Health Approach to Innovation\u201d. Background Paper 6.6. Ischaemic and Haemorrhagic Stroke","author":"Wittenauer R.","year":"2012"},{"key":"e_1_2_8_33_2","unstructured":"The World Health Organization The Top 10 Causes of Death 2017."},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12964"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1179\/1476830514Y.0000000127"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1159\/000085386"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2008.12.007"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21081009"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.2174\/1381612033391261"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(95)00055-b"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-007-9675-3"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5849(97)00430-9"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.10.1255"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/85.3.895"},{"key":"e_1_2_8_45_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151608.29217.62"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/74.2.227"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.05.047"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2009.08.009"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-012-0786-1"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-014-1311-5"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.01.014"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-010-0889-x"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2017.01.006"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.1080\/10715760600823128"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.07.026"},{"key":"e_1_2_8_56_2","doi-asserted-by":"publisher","DOI":"10.1385\/MN:31:1-3:135"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.10.068"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2060"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000029925.18593.5c"},{"key":"e_1_2_8_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200500019"},{"key":"e_1_2_8_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-9150(99)00207-5"},{"key":"e_1_2_8_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2004.09.021"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114510003958"},{"key":"e_1_2_8_64_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2010.00273.x"},{"key":"e_1_2_8_65_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.123927"},{"key":"e_1_2_8_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.08.073"},{"key":"e_1_2_8_67_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114515000136"},{"key":"e_1_2_8_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0049-3848(00)00321-2"},{"key":"e_1_2_8_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.10.022"},{"key":"e_1_2_8_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2003.12.010"},{"key":"e_1_2_8_71_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.1.317S"},{"key":"e_1_2_8_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68069-0"},{"key":"e_1_2_8_73_2","doi-asserted-by":"publisher","DOI":"10.4137\/CMC.S17071"},{"key":"e_1_2_8_74_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269881104047272"},{"key":"e_1_2_8_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2016.03.007"},{"key":"e_1_2_8_76_2","doi-asserted-by":"publisher","DOI":"10.2217\/fca.09.36"},{"key":"e_1_2_8_77_2","doi-asserted-by":"publisher","DOI":"10.1136\/heart.90.1.107"},{"key":"e_1_2_8_78_2","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bap024"},{"key":"e_1_2_8_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2012.10.008"},{"key":"e_1_2_8_80_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.007096"},{"key":"e_1_2_8_81_2","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2017.1285870"},{"key":"e_1_2_8_82_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu8050250"},{"key":"e_1_2_8_83_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.29.12.2467"},{"key":"e_1_2_8_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2009.01.008"},{"key":"e_1_2_8_85_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-1-200501040-00007"},{"key":"e_1_2_8_86_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000177587.76846.89"},{"key":"e_1_2_8_87_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwr226"},{"key":"e_1_2_8_88_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112010"},{"key":"e_1_2_8_89_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.023648"},{"key":"e_1_2_8_90_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.677500"},{"key":"e_1_2_8_91_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.003131"},{"key":"e_1_2_8_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2012.12.006"},{"key":"e_1_2_8_93_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31826aacfa"},{"key":"e_1_2_8_94_2","doi-asserted-by":"publisher","DOI":"10.2174\/1871524911313010004"},{"key":"e_1_2_8_95_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i17"},{"key":"e_1_2_8_96_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107711"},{"key":"e_1_2_8_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2014.06.003"},{"key":"e_1_2_8_98_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-014-0720-1"},{"key":"e_1_2_8_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2011.08.009"},{"key":"e_1_2_8_100_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.010926"},{"key":"e_1_2_8_101_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2011.64"},{"key":"e_1_2_8_102_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28202"},{"key":"e_1_2_8_103_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200303"},{"key":"e_1_2_8_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2013.12.014"},{"key":"e_1_2_8_105_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.156.6.637"},{"key":"e_1_2_8_106_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/76.3.560"},{"key":"e_1_2_8_107_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.31.10.2301"},{"key":"e_1_2_8_108_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009738"},{"key":"e_1_2_8_109_2","first-page":"97","article-title":"Polyphenols as potential therapeutical agents against cardiovascular diseases","volume":"57","author":"Curin Y.","year":"2005","journal-title":"Pharmacological Reports"},{"key":"e_1_2_8_110_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114510003910"}],"container-title":["Oxidative Medicine and Cellular Longevity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2017\/7467962.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2017\/7467962.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2017\/7467962","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T04:46:38Z","timestamp":1722919598000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2017\/7467962"}},"subtitle":[],"editor":[{"given":"Manuela","family":"Curcio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":110,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1155\/2017\/7467962"],"URL":"https:\/\/doi.org\/10.1155\/2017\/7467962","archive":["Portico"],"relation":{},"ISSN":["1942-0900","1942-0994"],"issn-type":[{"value":"1942-0900","type":"print"},{"value":"1942-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2017-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"7467962"}}