{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:02:23Z","timestamp":1783386143303,"version":"3.54.6"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Doctoral Research Fund of Guangdong Medical University","award":["B2014004"],"award-info":[{"award-number":["B2014004"]}]},{"name":"Doctoral Research Fund of Guangdong Medical University","award":["20171152"],"award-info":[{"award-number":["20171152"]}]},{"name":"Doctoral Research Fund of Guangdong Medical University","award":["20151256"],"award-info":[{"award-number":["20151256"]}]},{"name":"Doctoral Research Fund of Guangdong Medical University","award":["A2015481"],"award-info":[{"award-number":["A2015481"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["B2014004"],"award-info":[{"award-number":["B2014004"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["20171152"],"award-info":[{"award-number":["20171152"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["20151256"],"award-info":[{"award-number":["20151256"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["A2015481"],"award-info":[{"award-number":["A2015481"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["B2014004"],"award-info":[{"award-number":["B2014004"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["20171152"],"award-info":[{"award-number":["20171152"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["20151256"],"award-info":[{"award-number":["20151256"]}]},{"name":"Traditional Chinese Medicine Research Projects of Guangdong Province","award":["A2015481"],"award-info":[{"award-number":["A2015481"]}]},{"name":"Medical Research Fund of Guangdong Province","award":["B2014004"],"award-info":[{"award-number":["B2014004"]}]},{"name":"Medical Research Fund of Guangdong Province","award":["20171152"],"award-info":[{"award-number":["20171152"]}]},{"name":"Medical Research Fund of Guangdong Province","award":["20151256"],"award-info":[{"award-number":["20151256"]}]},{"name":"Medical Research Fund of Guangdong Province","award":["A2015481"],"award-info":[{"award-number":["A2015481"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic>To assess the benefits of different treatments that aim to prevent the endoscopic recurrence of Crohn\u2019s disease (CD) after ileal resection.<jats:italic>Methods.<\/jats:italic>Randomized controlled trials (RCTs) were searched from MEDLINE, Embase, and the Cochrane Central Database. All the included RCTs with an endoscopic recurrence outcome which was defined as Rutgeerts\u2019 score\u2009\u2265\u2009i2 have a duration of more than 1 year. The quality of the included RCTs was assessed by the Cochrane Risk of Bias Tool. Pairwise treatment effects were estimated through a Bayesian random effects network meta-analysis by using the OpenBUGS 1.4 software and reported as odds ratios (ORs) with a 95% credible interval (CI).<jats:italic>Results.<\/jats:italic>Fourteen RCTs (877 participants) were included. Two strategies were superior to placebo for preventing endoscopic recurrence of CD at 1 year after surgery: infliximab (d, \u22125.475; 95% CI, \u221210.47 to \u20131.632) and adalimumab (d, \u22127.273; 95% CI, \u221213.84 to \u22122.585). Nine strategies were not effective: budesnoid, mesalazine (in both high and low dose), azathioprine,<jats:italic>Tripterygium wilfordii,<\/jats:italic>mesalazine\u2009+\u2009infliximab, ornidazole, untreated intervention, and Lactobacillus GG.<jats:italic>Conclusions.<\/jats:italic>Except for infliximab and adalimumab, other strategies included in our analysis were not effective for preventing endoscopic recurrence of CD at 1 year after ileal resection.<\/jats:p>","DOI":"10.1155\/2017\/7896160","type":"journal-article","created":{"date-parts":[[2017,5,28]],"date-time":"2017-05-28T21:01:25Z","timestamp":1496005285000},"page":"1-8","source":"Crossref","is-referenced-by-count":9,"title":["Strategies for Preventing Endoscopic Recurrence of Crohn\u2019s Disease 1 Year after Surgery: A Network 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