{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:08:46Z","timestamp":1790845726364,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anemia"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The aim of this study was to investigate and determine the risk factors associated with poor growth among SCA children.<jats:italic>Methods.<\/jats:italic>A cross-sectional study was conducted in Kinshasa, the capital\u2019s country. The nutritional status was assessed using the Z scores of the anthropometric indices.<jats:italic>Results.<\/jats:italic>We gathered data on the 256 patients, 138 females (53.9%), who entered the study. The mean age at presentation was 8.4 \u00b1 4.9 years of age. Underweight, stunting, and wasting were found, respectively, in 47.7%, 10.5%, and 50.3% of SCA children. A history of hand-foot syndrome, more than 3 blood transfusions, being less than 12 months of age when receiving the first transfusion, more than two severe sickle crises per year, a medical history of severe infections, and the presence of hepatomegaly were associated with poor growth. When comparing sickle cell patients under 12 years of age (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">159<\/mml:mn><\/mml:math>) to a group of 296 age-matched children with normal Hb-AA, a significantly higher proportion of subjects with stunting and underweight were found among SCA.<jats:italic>Conclusion.<\/jats:italic>Nutritional status encountered in Congolese sickle cell children has been described for the first time in this study. A high prevalence of poor growth in SCA children was found in our study.<\/jats:p>","DOI":"10.1155\/2017\/7916348","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T16:06:15Z","timestamp":1485792375000},"page":"1-6","source":"Crossref","is-referenced-by-count":16,"title":["Factors Associated with Growth Retardation in Children Suffering from Sickle Cell Anemia: First Report from Central Africa"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5396-5223","authenticated-orcid":true,"given":"Aim\u00e9","family":"Lukusa Kazadi","sequence":"first","affiliation":[{"name":"Division of Paediatric Haemato-Oncology and Nephrology, Department of Paediatrics, University Hospital of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9 Makuala","family":"Ngiyulu","sequence":"additional","affiliation":[{"name":"Division of Paediatric Haemato-Oncology and Nephrology, Department of Paediatrics, University Hospital of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Lambert","family":"Gini-Ehungu","sequence":"additional","affiliation":[{"name":"Division of Paediatric Haemato-Oncology and Nephrology, Department of Paediatrics, University Hospital of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Marie","family":"Mbuyi-Muamba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-1170","authenticated-orcid":true,"given":"Michel Ntetani","family":"Aloni","sequence":"additional","affiliation":[{"name":"Division of Paediatric Haemato-Oncology and Nephrology, Department of Paediatrics, University Hospital of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the 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