{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:33:45Z","timestamp":1787319225105,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>\n                    <jats:italic>Purpose<\/jats:italic>\n                    . To evaluate primary trabeculectomy with adjunctive mitomycin-C (MMC) in diabetic patients without retinopathy with primary angle-closure glaucoma (PACG).\n                    <jats:italic>Design<\/jats:italic>\n                    . This is a retrospective case series comparison.\n                    <jats:italic>Participants<\/jats:italic>\n                    . This retrospective trial compared outcomes of 88 eyes that underwent trabeculectomy in patients with diabetes mellitus (DM) without retinopathy and in 97 patients without DM.\n                    <jats:italic>Methods<\/jats:italic>\n                    . In this study, the intraocular pressure (IOP), visual acuity, visual field, and postoperative complications were compared between the two groups. Qualified surgical success is defined as an IOP between 6 and 18\u2009mmHg with or without topical antiglaucoma medication.\n                    <jats:italic>Results<\/jats:italic>\n                    . After a follow-up of 5 years, the IOP decreased from a mean basal IOP of\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mn>27.8<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>7.3<\/mml:mn>\n                    <\/mml:math>\n                    \u2009mmHg to\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mn>15.0<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>5.6<\/mml:mn>\n                    <\/mml:math>\n                    \u2009mmHg in the DM group and from\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mn>27.3<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>6.0<\/mml:mn>\n                    <\/mml:math>\n                    \u2009mmHg to\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mn>12.4<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>5.3<\/mml:mn>\n                    <\/mml:math>\n                    \u2009mmHg in the control group. The mean number of antiglaucoma medications was\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mn>3.4<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>1.3<\/mml:mn>\n                    <\/mml:math>\n                    and\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                      <mml:mn>3.3<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>1.2<\/mml:mn>\n                    <\/mml:math>\n                    preoperatively (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.587<\/mml:mn>\n                    <\/mml:math>\n                    ) whereas it was\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                      <mml:mn>1.7<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>1.5<\/mml:mn>\n                    <\/mml:math>\n                    and\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                      <mml:mn>1.1<\/mml:mn>\n                      <mml:mo>\u00b1<\/mml:mo>\n                      <mml:mn>1.4<\/mml:mn>\n                    <\/mml:math>\n                    at the 5-year follow-up (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.049<\/mml:mn>\n                    <\/mml:math>\n                    ). The 5-year qualified surgical success rates were 42.9% and 65.4% for both groups (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.046<\/mml:mn>\n                    <\/mml:math>\n                    ; log-rank test). Encysted blebs were seen in 21 (23.9%) patients in the DM group and in 12 (12.4%) patients in the control group (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                      <mml:mi>P<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.041<\/mml:mn>\n                    <\/mml:math>\n                    ).\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . PACG patients with DM without retinopathy undergoing primary trabeculectomy with MMC may have a lower long-term surgical survival rate compared with patients without DM.\n                  <\/jats:p>","DOI":"10.1155\/2017\/7947854","type":"journal-article","created":{"date-parts":[[2017,2,26]],"date-time":"2017-02-26T16:01:51Z","timestamp":1488124911000},"page":"1-6","source":"Crossref","is-referenced-by-count":6,"title":["Long-Term Outcomes of Primary Trabeculectomy in Diabetic Patients without Retinopathy with Primary Angle-Closure Glaucoma"],"prefix":"10.1155","volume":"2017","author":[{"given":"Jian","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, The Second People\u2019s Hospital of Jinan, No. 148 Jingyi Road, Jinan 250001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9631-4551","authenticated-orcid":true,"given":"Miaomiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Second People\u2019s Hospital of Jinan, No. 148 Jingyi Road, Jinan 250001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Second People\u2019s Hospital of Jinan, No. 148 Jingyi Road, Jinan 250001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianrong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Second People\u2019s Hospital of Jinan, No. 148 Jingyi Road, Jinan 250001, 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