{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T10:51:52Z","timestamp":1782730312717,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To assess the safety and efficacy of Trabectome procedure in patients with preoperative intraocular pressure (IOP) of 30\u2009mmHg or higher. <jats:italic>Methods<\/jats:italic>. All patients who had underwent Trabectome stand-alone or Trabectome combined with phacoemulsification were included. Survival analysis was performed by using Kaplan-Meier, and success was defined as IOP\u2009\u2264\u200921\u2009mmHg, 20% or more IOP reduction from baseline for any two consecutive visits after 3 months, and no secondary glaucoma surgery. <jats:italic>Results<\/jats:italic>. A total of 49 cases were included with an average age of 66 (range: 13\u201391). 28 cases had Trabectome stand-alone and 21 cases had Trabectome combined with phacoemulsification. Mean IOP was reduced from a baseline of 35.6\u2009\u00b1\u20096.3\u2009mmHg to 16.8\u2009\u00b1\u20093.8\u2009mmHg at 12 months (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:msup><mml:mrow><mml:mn>0.01<\/mml:mn><\/mml:mrow><mml:mrow><mml:mo>\u2217<\/mml:mo><\/mml:mrow><\/mml:msup><\/mml:math>), while the number of medications was reduced from 3.1\u2009\u00b1\u20091.3 to 1.8\u2009\u00b1\u20091.4 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:msup><mml:mrow><mml:mn>0.01<\/mml:mn><\/mml:mrow><mml:mrow><mml:mo>\u2217<\/mml:mo><\/mml:mrow><\/mml:msup><\/mml:math>). Survival rate at 12 months was 80%. 9 cases required secondary glaucoma surgery, and 1 case was reported with hypotony at day one, but resolved within one week. <jats:italic>Conclusion<\/jats:italic>. Trabectome seems to be safe and effective in patients with preoperative IOP of 30\u2009mmHg or greater. Even in this cohort with high preoperative IOP, the end result is a mean IOP in the physiologic range.<\/jats:p>","DOI":"10.1155\/2017\/8248710","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T17:00:48Z","timestamp":1492534848000},"page":"1-9","source":"Crossref","is-referenced-by-count":17,"title":["Short-Term Clinical Results of Ab Interno Trabeculotomy Using the Trabectome with or without Cataract Surgery for Open-Angle Glaucoma Patients of High Intraocular Pressure"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7361-9379","authenticated-orcid":true,"given":"Handan","family":"Akil","sequence":"first","affiliation":[{"name":"Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA"},{"name":"Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3372-0026","authenticated-orcid":true,"given":"Vikas","family":"Chopra","sequence":"additional","affiliation":[{"name":"Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA"},{"name":"Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex S.","family":"Huang","sequence":"additional","affiliation":[{"name":"Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA"},{"name":"Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramya","family":"Swamy","sequence":"additional","affiliation":[{"name":"Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA"},{"name":"Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6493-5313","authenticated-orcid":true,"given":"Brian A.","family":"Francis","sequence":"additional","affiliation":[{"name":"Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA"},{"name":"Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.081224"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-013-2500-7"},{"key":"3","first-page":"1","volume":"28","year":"2010","journal-title":"Clinical Surgery Journal Ophthalmology"},{"key":"4","first-page":"149","volume":"106","year":"2008","journal-title":"Transactions of the American Ophthalmological Society"},{"key":"5","year":"1993"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31820bcfda"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.06.001"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12737"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S83958"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.06.046"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000212294.31411.92"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.03.032"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/IIO.0b013e31821e5da3"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3182311b92"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-016-0190-y"},{"key":"16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.17925\/EOR.2014.08.02.113","volume":"8","year":"2014","journal-title":"European Ophthalmic Review"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8248710.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8248710.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8248710.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T17:00:53Z","timestamp":1492534853000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/joph\/2017\/8248710\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":16,"alternative-id":["8248710","8248710"],"URL":"https:\/\/doi.org\/10.1155\/2017\/8248710","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}